Bartter syndrome(BS)is a rare inherited salt-losing renal tubular disorder characterized by secondary hyperaldosteronism with hypokalemia and hypochloremic metabolic alkalosis,and normal or low blood pressure.In severe cases,preterm delivery,hypovolemia,ventricular arrhythmia,rhabdo-myolysis,renal failure,growth failure and sensorineural deafness may occur.In recent years,research on BS has made significant progress.The Bartter Syndrome Consensus Working Group has performed a system-atic literature review,and based on evidence-based medicine,summarized aspects related to BS,including clinical manifestations and classification,diagnosis,treatment strategies,and management of complications.This consensus provides an important reference for the better diagnosis and treatment of BS.
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