Gliomas are the most common primary intracranial tumors in adults,among which high-grade glioma patients are characterized by short survival and poor prognosis.The diagnosis,treatment,evaluation of effective treatments,and prognosis prediction of high-grade gliomas are of great significance for improving pa-tient survival.Conventional enhanced magnetic resonance imaging has deficiencies in delineating tumor extent,identifying tumor progression and treatment-related changes.Therefore,there is a broad consensus to incorporate amino acid PET,and 18 F-FET PET inparticular,into the diagnostic and therapeutic process of high-grade gliomas.In this article,we review the new research progress of 18 F-FET PET in the diagnosis and treat-ment of adult high-grade glioma in recent years.
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