罕见病研究2024,Vol.3Issue(1) :136-143.DOI:10.12376/j.issn.2097-0501.2024.01.019

视雪综合征的研究进展

The Research Progress of Visual Snow Syndrome

余子 吴毅
罕见病研究2024,Vol.3Issue(1) :136-143.DOI:10.12376/j.issn.2097-0501.2024.01.019

视雪综合征的研究进展

The Research Progress of Visual Snow Syndrome

余子 1吴毅1
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作者信息

  • 1. 复旦大学附属华山医院康复医学科,上海 200040
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摘要

视雪综合征(VSS)是一种以全视野中持续出现闪烁光点为临床特征的视觉障碍疾病,可伴畏光、夜盲等视觉症状和偏头痛、焦虑、抑郁等非视觉症状.VSS在病程中可保持稳定或持续恶化,对患者的视觉体验和精神状态带来极大痛苦.目前其病理机制尚不明确,有学说提示可能与视觉中枢皮层兴奋性增加相关.病例报道显示抗癫痫药、彩色滤光片、经颅磁刺激等治疗手段可能有助于改善症状,但仍需进一步临床研究验证.本文将对VSS的研究进展进行系统介绍.

Abstract

Visual snow syndrome(VSS)is a visual-disturbance disease characterized by continuous flickering tiny dots in the entire visual field,sometimes with visual symptoms like photophobia or nyctalopia and non-visual symptoms such as anxiety and depression.VSS can remain stable or worsen,causing distress to patients'visual experience and mental state.The pathological mechanism of VSS is still unclear and a hy-pothesis indicates a relationship between VSS and increased cortical excitability of the visual cortex.Some case reports suggest anti-seizure medications,colored filters and TMS may help eliminate symptoms,but futh-er studies are required to verify these treatments.This review will systematically introduce what we know about VSS so far.

关键词

视雪/视雪综合征/偏头痛/罕见病

Key words

visual snow/visual snow syndrome/migraine/rare diseases

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基金项目

上海市"科技创新行动计划"医学创新研究专项项目(22Y31900203)

出版年

2024
罕见病研究

罕见病研究

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