RESEARCH PROGRESS ON IMPACT AND REGULATION STRATEGIES OF TYPICAL ANTIBIOTICS ON ANAEROBIC DIGESTION EFFICIENCY OF SLUDGE:A REVIEW
Anaerobic digestion is one of the most effective and eco-friendly technologies for resource utilization and harmless disposal of organic wastes.In recent years,antibiotics have been widely misused and enriched into sludge,which inevitably has a potential impact on the anaerobic digestion system of sludge.This study comprehensively investigated the effects of different antibiotics on the efficacy of anaerobic digestion of sludge under various environmental conditions(temperature,concentration,substrate,exposure mode,coexistence,etc.).The results showed that antibiotics were generally inhibitory and a few tended to promote and restore.The reason for this discrepancy could be attributed to the variability in the effects of antibiotics on cell structure disruption(e.g.,cell wall structure),metabolic pathways(e.g.,enzyme activity,extracellular polymer secretion),and adaptive mechanisms(quorum sensing systems).However,the adverse effects of antibiotics in the system could be effectively reduced,and anaerobic digestion efficacy could be enhanced by adopting physical(such as hydrothermal,ultrasound,etc.),chemical(such as advanced oxidation technologies,ozone,electrochemistry,etc.),biological(such as the addition of exogenous bioenzymes,materials to accelerate electron transfer,etc.),and combined(such as alkali heat,ultrasound-ozone,etc.)pretreatment methods.Finally,prospects for the optimization of pretreatment methods and the potential impacts of antibiotic migration on ecosystems were discussed,which could provide references for enhancing the efficacy of anaerobic digestion.
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