In order to assess the health risks of Cd-contaminated soil after remediation by use of nano-particles in case of in-cidental ingestion,laboratory experimental studies were carried out,which involved addition of nano-particles including na-no-hydroxyapatite(n-HAP),nano-Fe3O4 and modified nano-scale carbon black to the samples of brown soil contaminated by cadmium(Cd),with the nano-partcle dosages of 1,0％,1.5％and 2.0％,respectively.As for the assessment of the effect on human health in vitro gastrointestinal simulation solubility bio-availability research consortium(SBRC)was applied.The experimental results obtained showed that the three kinds of nano-particles above-mentioned could effectively reduce the Cd content extracted from DTPA in soil,among them,n-HAP was most effective;meanwhile,the bio-availability of Cd in the gastrointestinal phase was significantly reduced,and declined with the amount of nano-particles added;and the oral ingestion of Cd in the gastric bio-availability was greater than that in the intestinal bio-availability.The amount added of three kinds of nano-particles had a negative linear correlation with the bio-availability of Cd in the gastrointestinal phase,exerting the greater effect on the bio-availability of the intestinal phase.As a consequence,nano-particles remediation of soil significantly could reduce the non-carcinogenic health risk and carcinogenic health risk of Cd-contaminated soil,and the soil having been remediated had no notable non-carcinogenic health risk(HQ＜1),and carcinogenic risk(CR＜1x10-6),and the health risk to children was higher than adults.In conclusion,the nano-particles can effectively reduce the bio-availability of Cd in brown soil particles,thus mitigating the health risk in case of accidental ingestion.Thus the research achievements provide a scientif-ic basis for the health risk assessment of nano-particles applied to the remediation of Cd-contaminated soil.
关键词
纳米材料/SBRC/土壤Cd污染/生物可给性/人体健康风险
Key words
nano-particles/SBRC/Cd-contaminated soil/bio-accessibility/human health risk
维普
万方数据