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纳米材料修复Cd污染土壤的人体健康风险研究

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为评估纳米材料修复Cd污染土壤因偶然摄入导致的健康风险,该研究加入1.0%、1.5%、2.0%的纳米羟基磷灰石(n-HAP)、纳米四氧化三铁、改性纳米碳黑修复Cd污染棕壤,通过体外胃肠模拟法评估其对人体健康的影响.结果表明,3种纳米材料可有效降低土壤中DTPA提取态Cd含量,其中n-HAP效果最好;同时Cd的胃肠相生物可给性显著降低,并且随纳米材料添加量而降低,经口摄入的Cd胃相生物可给性均大于肠相.3种材料的添加量与胃肠相中Cd的生物可给性呈线性负相关,且对肠相生物可给性影响更大.纳米材料修复土壤显著降低了 Cd污染土壤的非致癌健康风险和致癌健康风险,修复后土壤不存在显著的非致癌健康风险(HQ<1)和致癌风险(CR<1×10-6),且对儿童的健康风险高于成人.因此,纳米材料能有效降低棕壤颗粒中Cd的生物可给性,从而缓解因偶然摄入导致的健康风险,为纳米材料修复Cd污染土壤的健康风险评估提供科学依据.
Study on Risks to Human Health of Remediation of Cd Contaminated Soil by Immobilization of Nano-particles
In order to assess the health risks of Cd-contaminated soil after remediation by use of nano-particles in case of in-cidental ingestion,laboratory experimental studies were carried out,which involved addition of nano-particles including na-no-hydroxyapatite(n-HAP),nano-Fe3O4 and modified nano-scale carbon black to the samples of brown soil contaminated by cadmium(Cd),with the nano-partcle dosages of 1,0%,1.5%and 2.0%,respectively.As for the assessment of the effect on human health in vitro gastrointestinal simulation solubility bio-availability research consortium(SBRC)was applied.The experimental results obtained showed that the three kinds of nano-particles above-mentioned could effectively reduce the Cd content extracted from DTPA in soil,among them,n-HAP was most effective;meanwhile,the bio-availability of Cd in the gastrointestinal phase was significantly reduced,and declined with the amount of nano-particles added;and the oral ingestion of Cd in the gastric bio-availability was greater than that in the intestinal bio-availability.The amount added of three kinds of nano-particles had a negative linear correlation with the bio-availability of Cd in the gastrointestinal phase,exerting the greater effect on the bio-availability of the intestinal phase.As a consequence,nano-particles remediation of soil significantly could reduce the non-carcinogenic health risk and carcinogenic health risk of Cd-contaminated soil,and the soil having been remediated had no notable non-carcinogenic health risk(HQ<1),and carcinogenic risk(CR<1x10-6),and the health risk to children was higher than adults.In conclusion,the nano-particles can effectively reduce the bio-availability of Cd in brown soil particles,thus mitigating the health risk in case of accidental ingestion.Thus the research achievements provide a scientif-ic basis for the health risk assessment of nano-particles applied to the remediation of Cd-contaminated soil.

nano-particlesSBRCCd-contaminated soilbio-accessibilityhuman health risk

邵雪、王利红、成杰民

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山东师范大学地理与环境学院,山东 济南 250358

山东省分析测试中心,山东 济南 250014

纳米材料 SBRC 土壤Cd污染 生物可给性 人体健康风险

国家自然科学基金国家自然科学基金

4187711941471255

2024

环境科学与技术
湖北省环境科学研究院

环境科学与技术

CSTPCD北大核心
影响因子:0.943
ISSN:1003-6504
年,卷(期):2024.47(4)
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