首页|左氧氟沙星在水环境中的赋存、风险及降解技术研究进展

左氧氟沙星在水环境中的赋存、风险及降解技术研究进展

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水环境中的抗生素不仅诱导微生物产生抗性基因(ARGs)及耐药细菌,而且危害生物安全,对人类生命健康产生严重威胁.氟喹诺酮类抗生素(FQs)及其引发的ARGs问题已引起国内外学者广泛关注.左氧氟沙星(LVFX)是使用最广泛的FQs之一,因生物体代谢率低且化学结构稳定,在环境中被广泛检出.因此亟需掌握LVFX在水环境中的赋存特征,厘清其对生态环境的危害,并比较分析现有技术对其去除效果.在现有研究基础上综述了 LVFX在水环境中的赋存特征,从诱导微生物产生ARGs和耐药细菌及威胁水生态安全两个方面阐述了 LVFX的生态风险,系统阐述了物理法、化学法和生物法去除LVFX的效果及研究进展,分析了这些技术的优缺点,以期为高效低耗降解LVFX并抑制ARGs的传播提供一定的参考.
A review on levofloxacin in aquatic environment:the concentration characteristics,risks and degradation technologies
Antibiotics in water environment not only induce resistance genes and drug-resistant bacteria,but also endanger the safety of ecology and threaten human life and health.Fluoroquinolones and relevanted antibiotic resistance genes(ARGs)have been widely concerned by scholars at home and abroad.Levofloxacin(ⅠVFX),one of the most widely used fluoroquinolones,is widely detected in the environment due to its low metabolic rate in life and stable chemical structure.Therefore,it is urgent to get the concentration characteristic of LVFX in the water environment,and clarifies its harm to the ecological environment,compares and analyzes the removal effects of existing technologies.Based on the existing researches,the occurrence characteristics of LVFX in water environment was summarized,and the ecological risk of LVFX from two aspects of inducing ARGs and drug-resistant bacteria and threatening the ecological safety of water was expounded.The effect and research progress of LVFX removal by physical,chemical and biological methods were reviewed,and the advantages and disadvantages of these methods were analyzed.The purpose was to provide some references for efficient degrading LVFX and inhibiting the spread of ARGs.

levofloxacinantibiotic resistance genesenvironmental riskstreatment technologies

卢洪斌、卢少勇、曾泽泉、黄张根

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中国科学院山西煤炭化学研究所,煤转化国家重点实验室,山西 太原 030001

中国环境科学研究院,湖泊水污染治理与生态修复技术国家工程实验室,环境基准与风险评估国家重点实验室,北京 100012

北京师范大学水科学研究院,北京 100875

左氧氟沙星 抗性基因 环境风险 处理技术

中国科学院山西煤炭化学研究所自主创新基金-基础研究项目山西省基础研究计划国家环境保护湖泊污染控制重点实验室开放基金唐山市水环境生态修复技术重点实验室开放基金科技部基础性工作专项

SCJC-WRW-2023-182022030212224042022HPYB-092015FY110900

2024

10.15985/j.cnki.1001-3865.2024.03.015

环境污染与防治
浙江省环境保护科学设计研究院

环境污染与防治

CSTPCD北大核心
影响因子：0.79
ISSN：1001-3865
年,卷(期)：2024.46(3)
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