Freshwater quality criteria of 3 non-steroidal anti-inflammatory drugs and their ecological risk assessment in China
Non-steroidal anti-inflammatory drugs are widely used and frequently detected in natural water bodies,which poses potential ecological risk on aquatic organisms.By collecting the toxicity data of 3 typical non-steroidal anti-inflammatory drugs such as ibuprofen,diclofenac and acetaminophen,the freshwater quality criteria were derived.Combined with the concentration data of 3 non-steroidal anti-inflammatory drugs in 7 river basins in China,the ecological risks were evaluated.Results showed that:(1)the acute toxicity data of ibuprofen involved 5 phyla and 8 species,and the toxicity data ranged from 1.65 to 1 381 mg/L;the chronic toxicity data involved 7 phyla and 15 species,and the toxicity data ranged from 0.001 to 70.0 mg/L.The acute toxicity data of diclofenac involved 4 phyla and 8 species,and the toxicity data ranged from 4.2 to 1 776 mg/L;the chronic toxicity data involved 6 phyla and 15 species,and the toxicity data ranged from 0.000 4 to 20.0 mg/L.The acute toxicity data of acetaminophen involved 6 phyla and 9 species,and the toxicity data ranged from 2 to 5 308.89 mg/L;the chronic toxicity data involved 7 phyla and 10 species,and the toxicity data ranged from 0.001 to 17.17 mg/L.(2)Based on the SSD curve,the short-term freshwater quality criteria of ibuprofen,diclofenac and acetaminophen were 786.29,1 034.52 and 798.15 μg/L,respectively;the long-term freshwater quality criteria of ibuprofen,diclofenac and acetaminophen were 4.58,0.52 and 6.37 μg/L,respectively.(3)The risk quotient method was used to evaluate ecological risks of ibuprofen,diclofenac and acetaminophen in 7 river basins in China.Results were that the risks of 3 non-steroidal anti-inflammatory drugs in China were not significant in general.
万方数据
维普
