Research progress on response mechanisms of soil bacterial flora under tetracycline antibiotics stress
Tetracycline antibiotics(TCs)have become the second most widely used antibiotics globally.They are extensively used in human disease treatment,animal husbandry,aquaculture,and other areas.However,the organisms face a lot of difficulty in the complete absorption of TCs;hence,a large portion of them is excreted and enters the environment through waste.TCs have been detected in a majority of environmental media in global ecosystems.In particular,when TCs residues in animal manure are used as organic fertilizers in farmland or when wastewater containing TCs residues is used for irrigation,TCs can accumulate in agricultural soil,leading to pollution.TCs pose risks to human health and the ecosystem through the food chain.The primary function of TCs is to inhibit the reproduction of bacteria.When they enter the soil as pollutants,they can affect the diversity,abundance,structure,and function of bacterial communities,leading to soil pollution and a decline in fertility.Therefore,this study aimed to explain the response mechanisms of bacterial communities in the soil to TCs pollution,focusing on the biomass,diversity,dominant bacterial groups,and enzyme activity of bacterial communities.It also highlighted the research gaps in exploring the changes in bacterial communities in the soil caused by TCs pollution and proposed critical research questions for future studies.