Optimization of antibiotic degradation efficiency during anaerobic digestion of swine manure using response surface method
To study interaction of the fermentation time,total solids and initial concentration on degradation efficiency during anaerobic digestion of swine manure,response surface methodology was used to find out optimal parameters to reduce antibiotic residual concentrations of sulfadimidine(SD)and sulfamethoxazole(SMX),by using the above three factors as independent variables and antibiotic residual concentration and gas production as response values.The results showed that the lowest residual concentration of SD was 0.428 mg·kg-1TS when there were 3%TS,40 mg·kg-1TS initial concentration and 30 d;the lowest residual concentration of SMX was 0.1063 mg·kg-1TS when there were 7%TS,40 mg·kg-1TS initial concentration and 20 d.The highest gas yield of swine manure with SD was 389.3 mL·kg-1TS when there were 5.58%TS,80 mg·kg-1TS initial concentration and 27.8 d;the highest gas yield of swine manure with SMX was 389.6 mL·kg-1TS when there were 5.88%TS,80 mgkg-1TS initial concentration and 30 d.This study provides theoretical and technical support for reducing antibiotic residues and increasing gas production during anaerobic digestion of swine manure.