Effects of short-term exposure to air pollution on recurrence of ischemic stroke and greenness modification effects in Tianjin
Objective To evaluate the effects of air pollutants on the recurrence of ischemic stroke in Tianjin residents,and to preliminarily explore the modification effect of greenness,so as to provide a scientific basis for relevant departments to formulate comprehensive prevention and control strategies and measures.Methods Daily data on air pollutants,meteorological conditions and the number of patients admitted for ischemic stroke recurrence in Tianjin from 2019 to 2021 were collected,and descriptive analysis and Spearman rank correlation analysis were performed.A nonlinear model of distribution lag(DLNM)was constructed,which was quantitatively assessed by the percentage change in the risk of ischemic stroke recurrence admission(ER)for every 10 µg/m3 increase in contaminant mass concentration.At the same time,the NDVI value was used as a greenness index to analyze the difference between air pollutants(lag01)and the risk of ischemic stroke recurrence at different green exposure levels.Results 34 964 people were admitted to hospitals for recurrent ischemic stroke in Tianjin,and the median daily admission volume was 31;Short-term exposure to NO2(lag 0-1,lag 01-03)was positively correlated with the number of hospital admissions for ischemic stroke recurrence,and the effect size was the largest when the cumulative lag was 2 days(ER=3.8％,95％CI:1.9％-5.8％);Short-term exposure to O3(lag 0-3,lag 01-03)was inversely associated with hospital admissions for ischemic stroke recurrence,with the largest effect size at a cumulative lag of 3 days(ER=-2.0％,95％CI:-3.3％--0.8％).Compared with low level of NDVI exposure,when NO2 concentration increased by 10 μg/m3 at high level of NDVI exposure,the risk of IS recurrence decreased,with ER changing from 3.56％to 3.55％;meanwhile,the protective effect of O3 against IS recurrence was also enhanced,with ER changing from-1.54％to-1.56％.Conclusion Short-term exposure to NO2 increases the risk of IS recurrence,and high levels of greenness exposure can reduce this risk.
万方数据
维普
