首页|基于仿真数据的多污染物健康效应估计方法学比较研究

基于仿真数据的多污染物健康效应估计方法学比较研究

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目的 探讨多污染物健康效应的估计方法.方法 收集北京市2015-2019年每日心血管疾病死亡数据和6种主要空气污染物浓度数据.基于对2种污染物权重和5种健康效应的10种组合下仿真的死亡数据,分别使用单污染物相加方法、累积风险指数(cumulative risk index,CRI)、监督主成分分析(supervised principal component analysis,SPCA)和贝叶斯多污染物加权模型(Bayes multi-pollutant weighted model,BMP)估计各空气污染物的健康效应及空气污染混合物的总效应,比较4种方法估计结果的准确性和稳定性.结果 在所有仿真组合中,单污染物相加方法均高估污染物的健康效应,而SPCA均低估污染物的健康效应.当仿真设定的健康效应较低时,BMP估计得最准确,且在所有仿真组合中,BMP估计值的标准差始终小于CRI方法,BMP估计的总效应的标准差是CRI的标准差的69%~96%.结论 BMP方法能够稳定估计多种空气污染物的健康效应,且估计结果可以合理解释污染物对人群健康的影响.
A comparative study on estimation methods of multi-pollutant health effects based on simulation data
Objective To explore the assessment method of multi-pollutants effectsat the same time.Methods The data of daily cardiovascular deaths and concentration of 6 main pollutants during 2015 to 2019 in Beijing were collected.Based on the simulated death data under 10 combinations of 2 pollutant weights and 5 health effects,4 approaches were compared in evaluating health risks of multi-pollutants:Single pollutant addition method,cumulative risk index(CRI),supervised principal component analysis(SPCA)and Bayes multi-pollutant weighted model(BMP).Results The standard methods always overestimated the health effects of pollutants,while SPCA methods always underestimated the effects.When the simulated health effects are low,the BMP was the most accurate,but the CRI estimate is closer to the real value when the setting effects are high.In all scenarios,the standard deviations(SD)of the health effects estimated by BMP were consistently smaller than CRI,the SD of the total effect estimated by BMP is 69%-96%of the SD of CRI.Conclusion The BMP method can estimate the health effects of pollutants stably,and the estimation results can reasonably explain the impact of pollutants on population health.

Multi-pollutantsSimulationCumulative risk indexSupervised principal component analysisBayes multi-pollutant weighted model

曹茹、王裕新、徐志虎、黄婧、李国星

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航天中心医院医务部,北京 100191

北京大学公共卫生学院劳动卫生学与环境卫生学系

帝国理工大学公共卫生学院环境健康系

多污染物 仿真 累计风险指数 监督主成分分析 贝叶斯多污染物加权模型

2024

环境与健康杂志
中华预防医学会,天津市疾病预防控制中心

环境与健康杂志

CSTPCD
影响因子:0.658
ISSN:1001-5914
年,卷(期):2024.41(8)