Effects of prenatal BPA exposure on maternal health and birth outcome:a review of recent studies
As an environmental estrogen,the adverse effects of bisphenol A(BPA)on human health and the ecological environment have raised concerns in researchers.Accumulating evidences suggest that prenatal exposure to BPA can have toxic effects on maternal health and fetal development.Animal studies have shown the biological basis for the adverse effects of BPA exposure on intrauterine development of the offspring,however,no concrete conclusion can be drawn from human studies at present.Nonetheless,most studies suggested that BPA exposure during pregnancy was associated with multiple pregnancy complications and adverse neonatal birth outcomes,mainly such as thyroid dysfunction in pregnancy,gestational diabetes,preeclampsia,as well as abnormal neonatal birth weight and gestational age.This review summarized the current research progress of BPA exposure assessment and the association between prenatal BPA exposure and maternal-neonatal health.Furthermore,standardization of the methods for BPA exposure analysis and large-scale cohort study are recommended for the unsolved issues.
万方数据
维普
