Environmental endocrine disruptors and bone health:a review of recent studies
With the acceleration of industrialization,environmental endocrine disruptors(endocrine disrupting chemicals,EDCs)have become a global environmental problem.EDCs are widely found in daily life,such as plastic products,pesticides,cosmetics and industrial chemicals,and can enter the human body through various ways.In recent years,the effects of EDCs on human health have attracted increasing attention,and the mechanism of interfering with the normal function of hormonal system may lead to reproductive system dysfunction,developmental abnormalities,damage of nervous system and bone health.Different types of EDCs will have different effects on bone density,bone microstructure,bone cell function and the mechanism of bone metabolic imbalance,causing potential harm to bone health.This paper intends to conduct a comprehensive review of the physicochemical properties of EDCs,their impact on the skeletal system and the potential mechanisms.By delving into the relationship between EDCs and skeletal health,we aim to better understand the potential hazards of EDCs to human health and provide a scientific basis for the development of effective preventive measures and therapeutic strategies.
Environmental endocrine disruptorsBone healthEnvironmental exposureBone metabolism imbalanceMechanism of action
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