Application of early staged pulmonary rehabilitation in lobectomy patients with severe lung cancer
Objective To analyze the effects of early staged lung rehabilitation on lung function,cancer-related fatigue and physical activity of patients with severe lung cancer after lobectomy.Methods A total of 112 patients with severe lung cancer who underwent pulmonary lobectomy in the Affiliated Cancer Hospital of Xinjiang Medical University from June 2019 to May 2020 were selected as study objects.They were divided into control group and observation group in the order of enrollment,with 56 cases in each group.There was no significant difference in baseline information between the two groups(P>0.05).The control group was given routine rehabilitation nursing,and the observation group was additionally given early staged lung rehabilitation on the basis of routine rehabilitation nursing.A follow-up study was conducted for 18 months.Pulmonary function indexes,such as forced expiratory volume in one second(FEV1)and forced expiratory volume in one second/forced vital capacity(FEV1/FVC),the incidence of cancer-related fatigue,daily physical activity time,Self-rating Anxiety Scale(SAS)scores and Self-rating Depression Scale(SDS)scores were compared between the two groups before intervention 1,6 and 18 months after intervention.Results The incidence of cancer-related fatigue in the observation group was significantly lower than that in the control group(44.64%vs.64.29%,P=0.037).Repeated measurement analysis of variance showed that there were significant differences in the FEV1,FEV1/FVC,daily physical activity time,SAS scores,and SDS scores between intra-subject effect and inter-subject effect(P<0.05),suggesting that FEV1,FEV1/FVC,daily physical activity time,SAS scores,and SDS scores had a trend of change over time,and there were differences between groups.At 1,6 and 18 months after intervention,FEV1,FEV1/FVC and daily physical activity time in the observation group were significantly higher than those in the control group,while SAS scores and SDS scores in the observation group were significantly lower than those in the control group(P<0.05).Conclusion Early staged pulmonary rehabilitation on the basis of conventional rehabilitation nursing can improve the long-term pulmonary function and negative emotions,reduce the incidence of cancer-related fatigue,and increase physical activity in patients with severe lung cancer after lobectomy.
Early staged pulmonary rehabilitation programLobectomySevere lung cancerLung functionCancer-related fatiguePhysical activity