Evaluation of endocrine indexes and sexual function levels in patients with benign prostatic hyperplasia combined with diabetes after transurethral resection of prostate
Objective To evaluate the endocrine indexes and sexual function levels in patients with benign prostatic hyperplasia(BPH)combined with diabetes after transurethral resection of prostate(TURP).Methods The clinical data of 100 patients with BPH who underwent TURP from January 2020 to January 2023 were retrospectively analyzed.Among them,30 patients suffered from diabetes(diabetes group),and the other 70 patients did not have diabetes(control group).Surgery related indexes were compared between the two groups.Fasting blood glucose(FBG),total cholesterol(TC),triglycerides(TG),low-density lipoprotein cholesterol(LDL-C),high-density lipoprotein cholesterol(HDL-C),glycated hemoglobin(HbAlc),follicle stimulating hormone(FSH),estradiol(E2),prolactin(PRL),luteinizing hormone(LH),and testosterone(T)were measured.Sexual function was evaluated using the Brief Male Sexual Function Inventory(BMSFI).The incidence of complications was investigated during six-month follow-up.Results There was no statistically significant difference in the age,body mass index(BMI),waist circumference,systolic blood pressure,diastolic blood pressure,prostatic volume,retention time of urinary catheters,surgical time,glandular resection quality,or intraoperative blood loss between the two groups(P>0.05).The FBG,HbAlc,TC,TG,LDL-C,and E2 in the diabetes group were higher than those in the control group,while the HDL-C and T in the diabetes group were lower than those in the control group(all P<0.05).There was no statistically significant difference in the FSH,LH,or PRL between the two groups(P>0.05).The diabetes group had lower scores in erection,libido,ejaculation,problem assessment,and overall satisfaction than the control group(P<0.05).The total incidence of complications in the diabetes group was higher than that in the control group(30.01%vs.11.44%,P<0.05).Conclusion It is abnormal of endocrine indicators in patients with benign prostatic hyperplasia combined with diabetes after TURP,and the risk of sexual dysfunction and complications is increased.Therefore,more attention should be paid to related clinical indicators.
DiabetesBenign prostatic hyperplasiaTransurethral resection of the prostateEndocrine indicatorsSexual dysfunction