In order to improve the stability and load capacity of expressway in the course of route design,this paper studies a new ex-pressway route design scheme.Taking Rende Expressway in Shandong Province as an example,the evaluation index system of route de-sign scheme is constructed to truthfully feedback the advantages and disadvantages of each link in the scheme.The evaluation model of route design scheme is formed by combining fuzzy comprehensive evaluation method with AHP,which is convenient for project manag-ers to choose suitable design scheme.The highway route design is completed by focusing on the local spiral line and avoiding the tunnel axis and fracture zone.The test results show that:with the route designed in this scheme,the cumulative settlement of the foundation is only 50 mm,and the average horizontal displacement of the whole structure is 2.47 mm,which indicates that the highway route scheme designed can effectively improve the cumulative settlement of the foundation,and also reduce the amount of foundation dis-placement.