摘要
节食可能导致人的行为及情绪发生变化,研究表明,部分肠道微生物会对人类行为及情绪产生作用,而饮食-肠道微生物-行为之间是否存在相关关系还没有得到深入研究.分析了不同人群的饮食习惯,将摄入物质分为高糖与高脂类、淀粉蛋白质类及蔬果维生素类,分别模拟这3 类物质在肠道系统消化过程中对微生物群落的影响,利用16s测序得到微生物的种群信息,采用问卷调查方法对节食人群表现出的行为及情绪进行统计分类,并对二者之间的关系进行分析.研究结果显示,经常摄入一类物质会对肠道微生物的丰度产生影响,部分关键微生物可对行为及情绪产生作用.将肠道微生物种群与人类行为关联起来,可为进一步确认肠道微生物对人类情绪变化影响提供数据支撑.
Abstract
Dieting can lead to changes in behavior and mood.Research has shown that some gut microbes play a role in human behavior and mood,but whether there is correlation between diet,gut microbes and behavior has not been thoroughly studied.The study analyzes the dietary habits of different groups;divides the intake substances into high sugar and high fat,starch and protein,and vegetables and fruits and vitamins;simulates the effects of these 3 types of substances on the microbial community in the digestive process of the intestinal system respectively;obtains the microbial population information by 16 s sequencing;statistically classifies the behaviors and emotions of dieting groups with questionnaire survey;and analyzes the relationship between them.The results show that regular intake of a class of substances can affect the abundance of gut microbes,and some of the key microbes can play a role in behavior and mood.Correlation of gut microbiome populations with human behavior can provide data support for further confirming the influence of gut microbiome on human mood change.
维普
万方数据