Hashimoto's thyroiditis is a common autoimmune disease characterized by the presence of thyroid-specific autoantibodies.It is characterized by the presence of thyroid-specific autoantibodies,and its pathogenesis is not fully understood.But it is related to the interaction of genetic,environmental and epigenetic factors.The development of the disease mainly involves cellular and humoral immunity,often with inflammatory infiltration of T cells and B cells.In histopathology,IL-23 is an important cytokine that plays a role in innate and adaptive immunity,and is a key factor in promoting inflammatory responses in multiple target organs.Resolvin E1(RvE1)is an endogenous lipid mediator derived from eicosapentaenoic acid(EPA)that has shown protective effects in many disease models.The study reviews the potential role of IL-23 and RvE1 in the regulation of Hashimoto's thyroiditis,so as to develop more accurate treatment,improve patients'quality of life,and reduce the risk of related complications.
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