The study extracts annabidiol(CBD)from industrial hemp flowers and leaves with ultrasonic assisted olive oil,and optimizes 4 factors of extraction process with central combination(CCD)method.The results indicates that the optimum conditions for CBD extraction are 95 W of ultrasonic power,62 ℃ of extraction temperature,45 minutes of extraction time,and a solid-liquid ratio of 1∶9(g/mL).The extraction yield is 91.35％,and the CBD content is 39.01 μg/mL under these conditions.This method offers the technological basis for a broad variety of applications of CBD.
维普
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