In order to better provide patients with personalized and accurate nursing services,meet patients'higher needs for nursing work,and improve patients'quality of life,the study selects 60 thyroid patients as research objects,randomly divides into control group and experimental group,with 30 cases in each group,and compares nursing intervention effect of the two groups.Personalized nursing can significantly shorten the postoperative bed time and hospital stay of thyroid surgery patients,and reduce the postoperative rehabilitation time of patients;significantly reduce the postoperative pain grade,wound infection rate and complication rate of thyroid surgery patients;significantly alleviate the patients'depression and anxiety,and improve the quality of nursing care and patients'satisfaction with nursing work.Personalized nursing has a positive effect on the postoperative rehabilitation of thyroid patients.