镁补充改善糖尿病患者血清胰岛素水平的Meta分析
Meta-analysis of the Efficacy of Magnesium Supplement for Serum Insulin Levels in Diabetes Patients
王春晓 1刘金宝 2孟妮佳 1李丽1
作者信息
- 1. 哈尔滨体育学院运动人体科学学院,哈尔滨 150008
- 2. 吉林水利电力职业学院,长春 130117
- 折叠
摘要
系统评价口服镁补充改善糖尿病患者血清胰岛素水平的效果.采用计算机检索PubMed、EBSCO、The Cochrane Library、CNKI、Web of Science数据库,搜集口服镁补充改善糖尿病患者血清胰岛素水平的相关研究,独立筛查文献、提取资料并评价纳入研究的偏倚风险后采用R studio软件进行Meta分析.亚组分析结果显示,口服镁补充在镁缺乏糖尿病患者中[SMD=-0.29,95％CI(-1.07,0.48),P＞0.01]、4～6 周补充周期[SMD=-0.74(-1.69,0.20),P＞0.01]、250～300 mg/d 剂量[SMD=-63(-1.25,0),P＜0.01]改善血清胰岛素水平效果更佳,说明口服镁补充对于改善糖尿病患者血清胰岛素水平具有良好的效果.
Abstract
The effect of oral magnesium supplementation on serum insulin level in diabetic patients was systematically evaluated.Databases,including PubMed,EBSCO,The Cochrane Library,CNKI and Web of Science,were searched to investigate the effect of oral magnesium supplementation on serum insulin level in diabetic patients.Papers were independently screened,data were extracted,and the risk of bias of included studies were assessed.Then Meta-analysis was performed with R studio software.The results of subgroups presented that,the effect of oral magnesium supplement is more obvious in magnesium-deficient patients[SMD=-0.29,95％CI(-1.07,0.48),P＞0.01],4～6 week duration time[SMD=-0.74(-1.69,0.20),P＞0.01],250～300 mg dosage[SMD=-63(-1.25,0),P＜0.01].The current evidence shows that,compared with control group,the oral magnesium supplement for diabetes patients can reduce serum insulin levels.
关键词
口服镁补充/糖尿病/血清胰岛素水平/微量元素/Meta分析/系统评价Key words
Oral magnesium supplement/Diabetes/Serum insulin level/Microelement/Meta-analysis/Systematic re-view引用本文复制引用
基金项目
黑龙江省自然基金项目(LH2023G005)
黑龙江省省属本科高校基本科研业务费项目(2023KYYWF-PY03)
黑龙江省省属本科高校基本科研业务费项目(2023KYYWF-TD06)
出版年
2024
NETL
NSTL
万方数据