In order to make the cable force optimization process of cable-stayed bridge more concise,the study proposes a method of cable force optimization of single-tower cable-stayed bridge based on hybrid algorithm.Based on the finite element simulation results of the bridge,the study selects the bridge state parameters,such as the displacement difference of the main beam and the deflection of the bridge tower,as the optimization objectives,and the cable force of the bridge as the control variable.The study displays the implicit functional relationship between the selected optimization objectives and the cable force of the bridge by the response surface method,identifies the optimal solution of the target by particle swarm optimization algorithm,and obtains the cable force of the single tower cable-stayed bridge after optimization.Based on the engineering application of a single tower cable-stayed bridge in North China,the results show that after the cable force optimization,the uniformity of the cable force and the bending moment of the main beam is greatly improved,the overall linear shape of the main beam is more ideal,and the effectiveness of the algorithm is verified.