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芪参益气滴丸在治疗冠心病心衰患者中的临床效果分析

Clinical Effect Analysis of Qishen Yiqi Drops in the Treatment of Heart Failure Patients with Coronary Artery Disease

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目的:研究芪参益气滴丸在冠心病心衰患者中的治疗效果,为临床提供依据.方法:回顾性分析2020年10月—2021年10月通许县人民医院收治的60例冠心病心衰患者的临床资料,采用随机数表法将患者分为观察组和对照组,每组各30例,其中对照组患者使用常规西药治疗,观察组患者则在西药基础上联合芪参益气滴丸进行治疗,对比两组患者治疗前后的治疗效果、心功能[左心室舒张末容积(LVEDV)、左室射血分数(LVEF)、心输出量(CO)、心率、前脑钠肽(NT-proBNP)、6 min步行实验]、生存质量的变化.结果:观察组患者的临床治疗效果(86.67%)高于对照组(56.67%),差异有统计学意义(χ2=6.648,P<0.05).治疗后,观察组患者LVEF高于对照组,LVEDV、NT-proBNP均低于对照组,差异有统计学意义(t=5.489、3.510、9.566,P<0.05);观察组患者CO、6 min步行实验结果高于对照组,心率低于对照组,差异有统计学意义(t=7.900、11.122、2.302,P<0.05);观察组患者的社会功能、躯体功能、角色功能生存质量评分均高于对照组,差异有统计学意义(t=5.743、5.547、6.649,P<0.05).结论:在冠心病心衰患者中,在西药的基础上联合芪参益气滴丸进行治疗能够有效提高治疗效果,并改善患者的心功能,调节LVEDV、LVEF、NT-proBNP等指标,从而提高其生存质量.
Objective:To study the therapeutic effect of Qishen Yiqi Drops in heart failure patients with coronary artery disease to provide a clinical basis.Methods:The clinical data of 60 patients with coronary heart failure admitted to the hospital from October 2020 to October 2021 were retrospectively analyzed,and the patients were divided into observation group and control group using the random number table method,with 30 cases in each group.The control group was treated with conventional Western medicine,while the observation group was treated with the combination of Qishen Yiqi Drops on top of Western medicine.The changes of treatment effect,cardiac function(left ventricular end-diastolic volume[LVEDV],left ventricular ejection fraction[LVEF],cardiac output[CO],heart rate,anterior brain natriuretic peptide[NT-proBNP],6 min walking test),and quality of survival were compared between the two groups before and after treatment.Results:The clinical treatment effect of patients in the observa-tion group(86.67%)was higher than that of the control group(56.67%),and the difference was statistically significant(χ2=6.648,P<0.05).After treatment,the LVEF of the observation group was higher than that of the control group,and LVEDV and NT-proBNP were lower than those of the control group,with statistically significant differences(t=5.489,3.510,9.566,P<0.05).The CO and 6 min walk experimental results of the observation group were higher than those of the control group,and the heart rate was lower than that of the control group,with statistically significant differences(t=7.900,11.122,2.302,P<0.05).The patients in the observation group had higher quality of survival scores for social,somatic,and role functions than the control group,with statistical-ly significant differences(t=5.743,5.547,6.649,P<0.05).Conclusion:In patients with coronary heart failure,combining Qishen Yiqi Drops with Western medicine can effectively improve the therapeutic effect and improve patients'cardiac function and regu-late LVEDV,LVEF,NT-proBNP and other indexes,thus improving their quality of survival.

Qishen Yiqi dropping pillsCoronary heart diseaseClinical efficacyHeart failure

张亚如、张西西

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河南省通许县人民医院心内科,河南 通许 475400

芪参益气滴丸 冠心病 临床疗效 心衰

河南省医学科技攻关计划

201900116

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(1)
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