Effect of Phased Nursing and Ovulation Promotion on the Condition Improvement in Infertile Patients with Obese Polycystic Ovarian Syndrome
Objective:To explore the application effect of applying staged care combined with ovulation promotion therapy in obese polycystic ovary syndrome infertility patients to provide a basis for clinical treatment.Methods:60 patients with obese polycystic ovary syndrome infertility admitted to the hospital from January 2019 to January 2021 were selected for the study,and the included patients were divided into control group and observation group based on the random number table method,with 30 cases in each group.The control group was given pharmacological ovulation treatment for 3 months after conventional nursing intervention,while the observation group was given pharmacological ovulation treatment after 3 months of phased care.The glucose metabolism index(fasting blood sugar[FPG],fasting resistance index[HOMA-IA]),sex hormone level(andorstenedione[T],luteinizing hormone[LH],follicle stimulating hormone[FSH]),coagulation and fibrinolysis index(coagulation factor Ⅷ[FⅧ],coagulation factor Χ[FⅩ])D-dimer[D-D],fibrinogen activetor inhibitor-1[PaI-1]),ovarian function and pregnancy outcome were compared between the two groups.Results:After the intervention,there was no statistically significant difference in the FPG index between the two groups(t=0.313,P＞0.05).The observation group had lower FINS and HOMA-IR indexes than the control group,and the differences were statistically significant(t=9.602,7.095,P＜0.05).After the intervention,T,LH,and FSH levels were lower in the observation group than in the control group,with statistically significant differences(t=4.005,7.875,5.775,P＜0.05).After the intervention,FⅧ,FⅩ,D-D,and PaI-1 indexes were significantly lower in the observation group than in the control group,with statistically significant differences(t=3.686,2.533,2.167,3.049,P＜0.05).After the intervention,the follicle development volume and follicle number in the observation group were significantly lower than those in the control group,and the endometrial thickness was higher than that in the control group,with statistically significant differences(t=5.455,4.383,4.013,P＜0.05).The pregnancy success rate was significantly higher in the observation group than in the control group,and the difference was statistically significant(χ2=4.267,P＜0.05).Conclusion:The application of staged care combined with ovulation promotion therapy in obese polycystic ovary syndrome infertile patients can improve glucose metabolism index,sex hormone level,coagulation and fibrinolytic index and ovarian function,and increase the pregnancy success rate.
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