Analysis of the Effect of Minimally Invasive Puncture and Drainage for Hypertensive Cerebral Hemorrhage in the Basal Ganglia Region on Neurological Function and Inflammatory Factors
Objective:To observe the therapeutic effect of minimally invasive puncture and drainage for the treatment of pa-tients with hypertensive cerebral hemorrhage in the basal ganglia region and the effect on neurological function and inflammatory factors,and to provide clinical reference.Methods:The general data of 80 patients with hypertensive cerebral hemorrhage in the basal ganglia region admitted to the hospital from May 2021 to May 2022 were retrospectively analyzed,and the patients were ran-domly divided into an observation group and a control group according to the lottery method,with 40 cases in each group.The con-trol group was treated with traditional craniotomy hematoma removal,and the observation group was treated with minimally invasive puncture drainage.The treatment effect and prognosis of the two groups were compared.Results:Surgical time,intraoperative bleeding,postoperative drainage time,and hospitalization time of the observation group were less than those of the control group,and the differences were statistically significant(t=5.441,64.328,19.382,56.502,P＜0.05).The serum neuron-specific enolase(NSE),S100 calcium-binding protein b(S100b),stroke scale(NIHSS),and modified Rakin scale(mRS)of the observation group were lower than those of the control group in the postoperative period,and the differences were statistically significant(t=18.503,11.363,60.164,20.012,P＜0.05).The levels of inflammatory factors such as tumor necrosis factor-α(TNF-α),interleukin-6(IL-6),IL-10,IL1β and other inflammatory factors in the postoperative observation group were lower than those in the control group,and the differences were statistically significant(t=10.684,4.510,11.326,6.074,P＜0.05).The hematoma clearance rate within 7 d postoperatively was higher than that of the control group,and the complication rate within 1 month postoperatively was lower than that of the control group,and the difference was statistically significant(t=57.535,5.741,P＜0.05).Conclusion:Mini-mally invasive puncture and drainage in patients with hypertensive cerebral hemorrhage in the basal ganglia region can enhance the therapeutic effect,which is of positive significance in improving the cerebral neurological function of the patients,improving the inflammatory response of the body,improving the clearance rate of hematoma,and reducing the risk of complications.
Hypertensive cerebral hemorrhage in basal gangliaMinimally invasive puncture and drainageNeurological func-tionInflammatory factorsHematoma clearance rate
NETL
NSTL
万方数据
