Clinical Efficacy of Bridging Therapy and Mechanical Thrombolysis Alone in Acute Anterior Circulation Large Vessel Occlusion Cerebral Infarction
Objective:To compare the clinical effects of bridging therapy and mechanical embolectomy in acute anterior circu-lation cerebral infarction.Methods:50 patients with acute anterior circulation large-vessel occlusive cerebral infarction admitted to the hospital from January 2021 to January 2022 were selected for the study,and were divided into the bridging group(n=25)and the pure mechanical thrombolysis group(n=25)according to the different surgical protocols.The revascularization,embolization-re-lated indexes,neurological recovery,prognosis,and complication rates were compared.Results:There was no statistically signifi-cant difference between the two groups in terms of revascularization and grade of revascularization(Z=-0.623,P>0.05).There was no statistically significant difference in the number of embolization and postoperative reperfusion between the two groups(χ2/t= 0.244,0.095,P>0.05).After surgery,there was no statistically significant difference between the NIHSS and mRS score groups of the two groups(t=0.034,0.415,P>0.05).The complication rate situation of patients in the mechanical thrombus extraction alone group was lower than that of the bridging group,and the difference was statistically significant(χ2=4.153,P<0.05).Conclusion:Surgical treatment of acute anterior circulation large-vessel occlusive cerebral infarction,the choice of bridging therapy and me-chanical thrombolysis alone both have excellent clinical efficacy and comparable efficacy.Mechanical thrombolysis alone can re-duce the incidence of intraoperative hemorrhagic transformation and achieve an ideal prognosis.
Acute precirculation large vessel occlusive cerebral infarctionBridgingSimple mechanical thrombectomyEfficacy