首页|经支气管镜介入冷冻方式对支气管结核患者痰菌转阴率的影响研究

经支气管镜介入冷冻方式对支气管结核患者痰菌转阴率的影响研究

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目的:探究经支气管镜介入冷冻方式对支气管结核患者痰菌转阴率的影响.方法:选取2021年1月—2022年1月南阳市第六人民医院收治的200例支气管结核患者作为研究对象,随机分为观察组(n=100,支气管镜介入冷冻治疗)和对照组(n=100,常规方案治疗),比较两组患者的治疗效果.结果:治疗后,观察组患者痰菌转阴情况优于对照组,差异有统计学意义(χ2=12.054,P<0.05);观察组患者症状消退时间明显短于对照组,差异有统计学意义(χ2=24.055、60.017、16.054、11.813,P<0.05);观察组患者各项肺功能水平优于对照组,差异有统计学意义(t=16.197、12.220、6.533,P<0.05);观察组患者血气水平明显优于对照组,差异有统计学意义(t=10.801、16.715、9.348,P<0.05);观察组患者并发症发生情况优于对照组,差异有统计学意义(χ2=7.354,P<0.05).结论:支气管结核患者采取支气管镜介入冷冻治疗,可有效改善其临床症状,提高痰菌转阴率,缩短治疗时间,改善肺功能和血气水平,并发症发生率较少,安全可靠.
Study of the Effect of Transbronchoscopic Interventional Freezing Modality on the Sputum Conversion Rate of Pa-tients with Bronchial Tuberculosis
Objective:To investigate the effect of transbronchoscopic interventional freezing modalities on sputum conversion rates in patients with bronchial tuberculosis.Methods:200 cases of bronchial tuberculosis patients admitted to the hospital from January 2021 to January 2022 were selected as the study subjects,and were randomly divided into the observation group(n=100,bronchoscopic interventional cryotherapy)and the control group(n=100,conventional regimen treatment).The treatment effects of patients in the two groups were compared.Results:After treatment,sputum bacterial conversion was better in the observation group than in the control group,and the difference was statistically significant(χ2=12.054,P<0.05).The time for symptoms to sub-side was significantly shorter in the observation group than in the control group,and the difference was statistically significant(χ2= 24.055,60.017,16.054,11.813,P<0.05).The blood gas level of the observation group was significantly better than that of the con-trol group,and the difference was statistically significant(t=10.801,16.715,9.348,P<0.05).The occurrence of complications in the two groups of patients was better in the observation group than in the control group,and the difference was statistically signifi-cant(χ2=7.354,P<0.05).Conclusion:Bronchoscopic interventional cryotherapy for bronchial tuberculosis patients can effectively improve their clinical symptoms,increase the rate of sputum bacterial conversion,shorten the treatment time,improve lung function and blood gas level,with less complication rate,safe and reliable.

BronchoscopyInterventional freezing methodBronchial tuberculosisSputum negative rate

高学英、张峡溦

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南阳市第六人民医院内镜室,河南 南阳 473000

支气管镜 介入冷冻方式 支气管结核 痰菌转阴率

河南省医学科技攻关计划

2019002615

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(2)
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