Exploration of the Effects of Different Blood Tablet Delivery Methods on the Results of Glucose-6-phosphate Dehy-drogenase Deficiency Testing in Newborn Infants in Shantou City
Objective:To understand the effect of different blood tablet delivery methods on glucose-6-phosphate dehydroge-nase(G6PD)deficiency test results in neonates in Shantou City.Methods:126 249 neonates born in Shantou City from January 1,2019 to December 31,2020 were selected as the study subjects.Heel blood was collected from newborns who had been born for 72 h and had breastfed more than 8 times,and dried blood samples were prepared on blood filter paper,which was divided into a group of specimens sent by hand and a group of specimens sent by ordinary courier according to the mode of delivery.G6PD was measured by fluorescence quantification,and peripheral blood was collected after screening for positive recall,and the diagnosis was confirmed by the G6PD/6PGD ratio method.Results:The mean number of days from blood film collection time to receipt time in the group sent to deliver specimens by hand was significantly shorter in the group with ordinary courier delivery of specimens,and the difference was statistically significant(u=513,P＜0.05).The screening positivity rate was significantly higher in the group with specimens delivered by ordinary courier than in the group with specimens sent by hand,and the difference was statistically significant(χ2=15.568,P＜0.05).There was no statistically significant difference in the rate of confirmation of diagnosis in the group of specimens delivered by ordinary courier compared with the group of specimens sent by hand(χ2=1.355,P＞0.05).Conclu-sion:The rate of G6PD screening positivity is significantly higher for specimens delivered by regular courier than for specimens de-livered by sending a person to deliver the specimen,and the rate of false positives is high for specimens delivered by regular courier.
NETL
NSTL
万方数据
