Objective:To investigate the efficacy and safety of transcatheter interventional intra-arterial thrombolysis for the treatment of severe freezing cold injury of the extremities.Methods:45 cases of patients with severe freezing cold injuries of the extremities hospitalized in the hospital were selected as the study subjects,and they were divided into 22 cases in the interven-tion group and 23 cases in the conventional group according to the different means of treatment.The conventional group was treat-ed with rapid rewarming,and the intervention group was combined with transcatheter arterial infusion thrombolytic agent thrombo-lytic treatment on the basis of the conventional group.The effectiveness of interventional therapy,complications and healing time and amputation rate were compared between the two groups.Results:The angiographic efficacy of the intervention group was bet-ter than that of the conventional group,and the difference was statistically significant(x2=4.896,P＜0.05).After taking appropriate interventions,the healing time and amputation rate of the intervention group were lower than those of the conventional group,and the difference was statistically significant(t=5.543;x2=4.811,P＜0.05).After treatment,the incidence of thrombolytic complica-tions was higher in the interventional group than in the conventional group in terms of the incidence of bleeding,and the difference was statistically significant(x2=5.626,P＜0.05).Conclusion:Transcatheter catheter arterial infusion of thrombolytic agents for the treatment of severe freezing cold injuries of the extremities has shown outstanding efficacy in promoting healing and minimizing am-putations in freezing cold injuries.
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