Racial Differences in the Prevalence and Genotype Distribution of HPV Infection in Gansu Linxia Area
Objective:To investigate the human papillomavirus(HPV)infection and genotype distribution among Han,Hui and Dongxiang women in Linxia,Gansu,and to provide a theoretical basis for the prevention and treatment of HPV infection and cervical cancer in this region.Methods:A total of 1 154 women(636 Han,276 Hui,and 242 Dongxiang)attending the hospital from October 2019 to April 2020 were selected for the study.Cervical epithelial cells were collected and tested for HPV infection status using PCR-reverse hybridization.The differences in HPV infection among different ethnic groups were compared for significance.Results:The positive detection rate of HPV among women in Linxia was 10.49%,and the positive rates of Hui and Dongxiang(11.59% and 12.40%,respectively)were higher than those of Han women(9.30%),with no statistically significant difference(P＞0.05).The HPV genotypes with the highest infection rates in Linxia were,in order,HPV16,HPV58,HPV52,HPV18,and HPV68,and the types of HPVs infected vary slightly among different ethnic groups.HPV infections in the three ethnic groups were analyzed at different ages,and the prevalence of HPV infection increased progressively with age,reaching a maximum at≥56 years of age.Conclusion:There are differences in HPV infection rates and subtypes of infection among Han,Hui,and Dongxiang women,and HPV infection in all three ethnic groups tends to increase with the age of the patient,with infection rates of about 11% in the 36-45 and 46-55 year-old age groups,which is most representative of HPV infection in the Linxia area.
Human papillomavirusInfection rateGenotypeRacial differences
万方数据
维普
