首页|超声雾化利多卡因吸入在FOB辅助经鼻清醒气管插管中的应用

超声雾化利多卡因吸入在FOB辅助经鼻清醒气管插管中的应用

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目的:观察超声雾化利多卡因吸入在纤维支气管镜(FOB)辅助经鼻清醒气管插管中的麻醉效果,期望为临床干预提供帮助.方法:选取2021年3月—2022年1月宁夏医科大学总医院收治的80例需行清醒气管插管的患者,按照随机数表法将其分为实验组和对照组;实验组采用利多卡因超声雾化联合右美托咪定麻醉,对照组采用传统的2%利多卡因喷喉联合右美托咪定麻醉.记录患者入室后(T1)、插管前5 min(T2)、插管后1 min(T3)及插管后5 min(T4)的心率(HR)、平均动脉压(MAP)、脉搏血氧饱和度(SPO2)、插管时间及首次插管成功率、呼吸抑制发生率、呛咳及体动发生率、术后满意度情况.结果:实验组在 T3、T4 时间点上 MAP 和 HR 较对照组低,差异有统计学意义(t=-11.06、-6.33、-9.76、-6.81,P<0.05).与对照组相比,实验组插管时间较短,首次插管成功率高,呼吸抑制、呛咳及体动发生率均低,差异有统计学意义(t=-6.37;χ2=8.41、-9.73、-4.83、-5.96,P<0.05).实验组插管满意度(69.1%)较对照组(57.4%)相比明显提高,差异有统计学意义(χ2=-4.37,P<0.05).结论:超声雾化利多卡因吸入联合右美托咪定对FOB辅助经鼻清醒气管插管的麻醉方案在插管过程中血流动力学波动较小、插管不良反应发生率低、患者满意度明显提高.
Ultrasound-nebulized Lidocaine Inhalation in FOB-assisted Transnasal Awake Tracheal Intubation
Objective:To observe the anesthetic effect of ultrasonically nebulized lidocaine inhalation in FOB-assisted transnasal awake tracheal intubation,with the expectation that it will be useful for clinical intervention.Methods:80 patients admitted to the hospital from March 2021 to January 2022 who required awake tracheal intubation were selected and divided into experimental group and control group with random table method.The experimental group was anesthetized with lidocaine ultrasonic nebulization combined with dexmedetomidine,and the control group was anesthetized with conventional 2%lidocaine throat spray combined with dexmedetomidine.Heart rate(HR),mean arterial pressure(MAP),pulse oximetry(SPO2),time of intubation and success rate of first intubation,incidence of respiratory depression,incidence of choking and somatic movements,and postoperative satisfaction were recorded after the patients admitted to the room(T1),5 min before intubation(T2),1 min after intubation(T3),and 5 min after intubation(T4).Results:The experimental group had lower MAP and HR at T3 and T4 time points than the control group,and the difference was statistically significant(t=-11.06,-6.33,-9.76,-6.81,P<0.05).Compared with the control group,the experimental group had a shorter intubation time,a higher success rate of first-time intubation,and a lower incidence of respiratory depression,choking,and body movement,with statistically significant differences(t=-6.37;χ2=8.41,-9.73,-4.83,-5.96;P<0.05).Satisfaction with intubation was significantly higher in the experimental group(69.1%)compared to the control group(57.4%),and the difference was statistically significant(χ2=-4.37,P<0.05).Conclusion:The anesthetic protocol of ultrasonically nebulized lidocaine inhalation combined with dexmedetomidine for FOB-assisted transnasal awake tracheal intubation showed less hemodynamic fluctuations during intubation,a low incidence of intubation adverse events,and significant higher patient satisfaction.

LidocaineDexmedetomidineUltrasonic atomizationAwake tracheal intubation

王慧、王志华、闵红星

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宁夏医科大学总医院麻醉科,宁夏 银川 750004

利多卡因 右美托咪定 超声雾化 清醒气管插管

宁夏医科大学校级课题宁夏自然科学基金

XZ20190082021AAC03331

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(4)
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