Ultrasound-nebulized Lidocaine Inhalation in FOB-assisted Transnasal Awake Tracheal Intubation
Objective:To observe the anesthetic effect of ultrasonically nebulized lidocaine inhalation in FOB-assisted transnasal awake tracheal intubation,with the expectation that it will be useful for clinical intervention.Methods:80 patients admitted to the hospital from March 2021 to January 2022 who required awake tracheal intubation were selected and divided into experimental group and control group with random table method.The experimental group was anesthetized with lidocaine ultrasonic nebulization combined with dexmedetomidine,and the control group was anesthetized with conventional 2%lidocaine throat spray combined with dexmedetomidine.Heart rate(HR),mean arterial pressure(MAP),pulse oximetry(SPO2),time of intubation and success rate of first intubation,incidence of respiratory depression,incidence of choking and somatic movements,and postoperative satisfaction were recorded after the patients admitted to the room(T1),5 min before intubation(T2),1 min after intubation(T3),and 5 min after intubation(T4).Results:The experimental group had lower MAP and HR at T3 and T4 time points than the control group,and the difference was statistically significant(t=-11.06,-6.33,-9.76,-6.81,P<0.05).Compared with the control group,the experimental group had a shorter intubation time,a higher success rate of first-time intubation,and a lower incidence of respiratory depression,choking,and body movement,with statistically significant differences(t=-6.37;χ2=8.41,-9.73,-4.83,-5.96;P<0.05).Satisfaction with intubation was significantly higher in the experimental group(69.1%)compared to the control group(57.4%),and the difference was statistically significant(χ2=-4.37,P<0.05).Conclusion:The anesthetic protocol of ultrasonically nebulized lidocaine inhalation combined with dexmedetomidine for FOB-assisted transnasal awake tracheal intubation showed less hemodynamic fluctuations during intubation,a low incidence of intubation adverse events,and significant higher patient satisfaction.