Study of the Correlation Between Peak Oxygen Uptake and Clinical Data in Patients with Type 2 Diabetes Mellitus
Objective:To investigate the correlation between peak oxygen uptake and clinical data in patients with type 2 dia-betes mellitus(T2DM).Methods:138 cases of T2DM patients admitted to the hospital from March 2019 to March 2022 were se-lected as study subjects.The correlation between peak oxygen uptake detected by cardiopulmonary exercise test(CPET)and clini-cal data was explored.Correlation coefficients were expressed as 0＜|r|≤0.3 suggests a weak correlation,0.3＜|r|≤0.7 suggested a moderate correlation,and 0.7<|r|≤1 suggested a strong correlation.Multiple linear regression was used to analyze the independent influences on peak oxygen uptake in patients with T2DM.Results:Peak oxygen uptake in patients with T2DM was weakly and negatively correlated with body mass index(BMI),waist circumference,and duration of T2DM,and the difference was statistically significant(r=-0.214,-0.250,-0.230,P＜0.05).Peak oxygen uptake in T2DM patients was weakly positively correlated with male sex and HDL-C,with statistically significant differences(r=0.120,0.220,P＜0.05),moderately strongly positively correlated with grip strength/body mass,with statistically significant differences(r=0.389,P＜0.05),and moderately strongly negatively correlated with left ventricular diastolic dysfunction(LVDD),with statistically significant(r=-0.321,P＜0.05).The results of multiple linear regression analysis suggested that LVDD and waist circumference were independent risk factors for peak oxygen uptake in patients with T2DM,and grip strength/body mass and male gender were independent protective factors for peak oxygen uptake in patients with T2DM.Conclusion:LVDD and waist circumference are independent risk factors for peak oxygen uptake in patients with T2DM,and grip strength/body mass and male gender are independent protective factors for peak oxygen uptake in patients with T2DM,and reduced grip strength/body mass in patients with T2DM increases the risk of impaired cardiorespiratory endurance.The study provides a simple and convenient method for predicting impaired cardiorespiratory endurance in patients with T2DM,and a theoretical basis for the prevention and treatment of impaired cardiorespiratory endurance in patients with T2DM.
Type 2 diabetesGrip strength/body massPeak oxygen uptakeIndependent influencing factors
万方数据
维普
