Clinical Study of Dopamine in Improving Hemodynamics in Patients Undergoing Intrathecal Anesthesia for Cesarean Delivery
Objective:To observe the effect of dopamine(DA)for intrathecal anesthesia for cesarean delivery on improving pa-tients'hemodynamics.Methods:130 patients who underwent elective cesarean delivery in the hospital from March 2021 to March 2022 were selected as the study subjects,and they were divided into the conventional group(65 patients with conventional intrathecal anesthesia)and the study group(65 patients with DA-assisted intrathecal anesthesia)in the ratio of 1:1 by using the lottery method.The intraoperative and postoperative hemodynamic changes,neonatal umbilical artery blood gases,and maternal and infant outcomes were compared between the two groups.Results:Postoperatively,the heart rate(HR),systolic blood pressure(SBP),diastolic blood pressure(DBP),and mean arterial pressure(MAP)of the study group were lower than those of the conventional group,and the oxygen saturation(SPO2)was higher than that of the conventional group,with statistically significant differences(t=2.514,2.929,3.474,3.409,2.857,P＜0.05).Under different anesthesia protocols,the arterial partial pressure of oxygen(PaO2)in the umbilical artery blood of neonates within the study group was higher than that of the conventional group,and the acid-base value(pH)and arterial partial pressure of carbon dioxide(PaCO2)were lower than that of the conventional group,and the differences were statistically significant(t=3.779,4.326,3.353,P＜0.05).The Apgar scores at 1 min,5 min,and 10 min after delivery were higher than those of the conventional group,and the differences were statistically significant(t=2.932,3.955,2.472,P＜0.05).Under different anesthesia protocols,the incidence of postoperative adverse events in patients within the study group was lower than that in the conventional group,and the difference was statistically significant(χ2=6.432,P＜0.05).Conclusion:The use of DA-assisted intrathecal anesthesia can effectively maintain intraoperative and postoperative hemodynamic stability in patients undergoing cesarean delivery,which is of positive significance in improving neonatal umbilical artery blood gas and prognosis,and reducing the risk of maternal postoperative adverse events.
Cesarean sectionIntraspinal anesthesiaDopamineHemodynamicsUmbilical artery blood gas analysisMaternal and infant outcomes
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维普
