Study on the Application Effect of Cerium Oxide-loaded Polycaprolactone Wound Dressing in Neurosurgical Postoperative Care
Objective:To investigate the application effect of cerium oxide-loaded polycaprolactone wound dressing in postoperative wound care after craniotomy in Neurosurgery Department,and to provide a basis for clinical postoperative care and reduction of complication rate.Methods:124 patients who underwent neurosurgical craniotomy admitted to the hospital from Febru-ary 2021 to December 2022 were selected as the study subjects,and they were divided into a control group and an experimental group according to the odd-even number of hospitalization number,with 62 cases in each group.The surgical wounds of patients in the control group were covered with traditional surgical dressings,and patients in the experimental group were covered with cerium oxide-loaded polycaprolactone dressings.The positive rate of healed wounds,the wound healing ratio,the average bleeding volume of wound dressing change and the occurrence of adverse reactions were compared between the two groups of patients.Results:The positive culture rate of sterile swabs of patients in the experimental group was significantly lower than that of the control group on day 2,day 4,and day 6 postoperatively,and the difference was statistically significant(χ2=4.888,4.593,5.962,P＜0.05).The wound sterile swab culture ratio of patients in the experimental group was significantly lower than the control group on day 0,day 2,day 4,and day 6 postoperatively,and the difference was statistically significant(χ2=-2.813,2.552,2.544,5.555,P＜0.05).The average bleeding volume of wound dressing change of patients in the experimental group was which was significantly lower than the control group,and the difference was statistically significant(t=2.555,P＜0.05).The incidence rate of adverse reactions in patients in the experimental group was was significantly lower than the control group,and the difference was statistically significant(χ2= 8.798,P＜0.05).Conclusion:Application of cerium oxide-loaded polycaprolactone wound dressing in neurosurgical postcranioto-my wound care reduces patients'wound sterile swab culture positivity rate,wound healing ratio,average bleeding at wound dressing changes,and incidence of adverse events.
万方数据
维普
