摘要
目的:探讨氧化铈负载聚己内酯创面敷料在神经外科开颅患者术后伤口护理中的应用效果,为临床术后护理及降低并发症发生率提供依据.方法:选取2021年2月—2022年12月哈尔滨医科大学附属第四医院收治的124例接受神经外科开颅手术的患者作为研究对象,根据住院号的奇偶数将其分为对照组和实验组,每组各62例.对照组患者的手术伤口采用传统外科敷料进行覆盖,实验组患者使用氧化铈负载聚己内酯敷料进行覆盖,比较两组患者伤口无菌拭子培养阳性率、伤口愈合比值、伤口换药平均出血量和不良反应发生情况.结果:实验组患者术后第2天、第4天、第6天的伤口无菌拭子培养阳性率明显低于对照组,差异有统计学意义(χ2=4.888、4.593、5.962,P＜0.05).术后当天、第2天、第4天、第6天,实验组患者的伤口愈合比值明显低于对照组,差异有统计学意义(χ2=-2.813、2.552、2.544、5.555,P＜0.05).实验组患者伤口换药平均出血量明显低于对照组,差异有统计学意义(t=2.555,P＜0.05).实验组患者不良反应发生率明显低于对照组,差异有统计学意义(χ2=8.798,P＜0.05).结论:在神经外科开颅患者术后的伤口护理中应用氧化铈负载聚己内酯创面敷料,能够降低患者伤口无菌拭子培养阳性率、伤口愈合比值、伤口换药平均出血量及不良反应发生率.
Abstract
Objective:To investigate the application effect of cerium oxide-loaded polycaprolactone wound dressing in postoperative wound care after craniotomy in Neurosurgery Department,and to provide a basis for clinical postoperative care and reduction of complication rate.Methods:124 patients who underwent neurosurgical craniotomy admitted to the hospital from Febru-ary 2021 to December 2022 were selected as the study subjects,and they were divided into a control group and an experimental group according to the odd-even number of hospitalization number,with 62 cases in each group.The surgical wounds of patients in the control group were covered with traditional surgical dressings,and patients in the experimental group were covered with cerium oxide-loaded polycaprolactone dressings.The positive rate of healed wounds,the wound healing ratio,the average bleeding volume of wound dressing change and the occurrence of adverse reactions were compared between the two groups of patients.Results:The positive culture rate of sterile swabs of patients in the experimental group was significantly lower than that of the control group on day 2,day 4,and day 6 postoperatively,and the difference was statistically significant(χ2=4.888,4.593,5.962,P＜0.05).The wound sterile swab culture ratio of patients in the experimental group was significantly lower than the control group on day 0,day 2,day 4,and day 6 postoperatively,and the difference was statistically significant(χ2=-2.813,2.552,2.544,5.555,P＜0.05).The average bleeding volume of wound dressing change of patients in the experimental group was which was significantly lower than the control group,and the difference was statistically significant(t=2.555,P＜0.05).The incidence rate of adverse reactions in patients in the experimental group was was significantly lower than the control group,and the difference was statistically significant(χ2= 8.798,P＜0.05).Conclusion:Application of cerium oxide-loaded polycaprolactone wound dressing in neurosurgical postcranioto-my wound care reduces patients'wound sterile swab culture positivity rate,wound healing ratio,average bleeding at wound dressing changes,and incidence of adverse events.
基金项目
黑龙江省卫生健康委科研课题项目(2020-089)
维普
万方数据