Perinatal GBS Infection in Pregnant Women,and its Correlation with Adverse Pregnancy Outcomes and Neonatal Outcomes
Objective:To analyze the infection of group B streptococcus(GBS)in perinatal pregnant women and its correlation with adverse pregnancy and neonatal outcomes.Methods 1 590 pregnant women at 36 to 42 weeks of gestation who were treated the hospital from November,2021 to March,2023 were selected as the research objects.GBS infection status of pregnant women during the perinatal period was detected and counted.The pregnant women were divided into groups according to GBS infection.The influencing factors of GBS infection in perinatal pregnant women were analyzed by logistic regression.The adverse pregnancy outcomes and neonatal outcomes of the two groups were compared,and the neonatal outcomes of the two groups were compared.Re-sults Among 1 590 perinatal pregnant women,84(5.28%)were GBS positive and 1 506(94.72%)were GBS negative.There was no significant difference in the average age,average gestational weeks and average parity between the positive group and the nega-tive group(P>0.05).There were statistically significant differences in body mass index(BMI),vaginitis and abnormal glucose tolerance during pregnancy between the two groups(t/x2=9.373,35.860,22.236;P<0.05).Logistic multivariate regression analysis showed that BMI,vaginitis and abnormal glucose tolerance in early pregnancy were independent risk factors for GBS infection in perinatal women(P<0.05).The incidence of premature rupture of membranes,intrauterine infection,puerperal infection and post-partum hemorrhage in the positive group was significantly higher than that in the negative group(x2=6.939,24.067,27.741,35.902;P<0.05).The incidence of fetal distress,premature birth,neonatal pneumonia,meningitis,septicemia,and pathological jaundice in the positive group were significantly higher than those in the negative group(x2=5.434,52.989,9.394,17.940,17.940,7.354;P<0.05).Conclusion GBS infection in perinatal pregnant women can significantly increase the risk of adverse pregnancy outcomes.Therefore,routine screening of GBS in perinatal pregnant women should be carried out to improve the safety of mother and child.Pregnant women infected with GBS should be intervened as soon as possible to improve adverse pregnancy outcomes.
Perinatal periodGroup B streptococcusAdverse pregnancy outcomesPremature rupture of membranesFetal dis-tress in uteroPremature rupture of fetal membranes