Study of the Effect of Glucagon Insulin Combined with Novolin r on Blood Glucose Levels and Insulin Function in Patients with Type 2 Diabetes Mellitus
Objective:To explore the effect of glucagon insulin combined with novolin r on blood glucose levels and insulin function in patients with type 2 diabetes mellitus(T2DM).Methods:82 cases of T2DM patients admitted to the hospital from June 2020 to December 2021 were selected as the study subjects,and were divided into the observation group and the control group according to the method of random number table,with 41 cases in each group.The control group was treated with Novolin R,and the observation group was treated with Glycine Insulin combined with Novolin R.Continuous treatment for 12 weeks.The blood glucose level,insulin function,inflammatory factor level,blood glucose attainment rate and the occurrence of hypoglycemia were compared between the two groups.Results:After treatment,the levels of FPG,2 hPG,and HbAlc in the observation group were lower than those in the control group,and the difference was statistically significant(t=2.110,4.437,12.109;P＜0.05).After treatment,the levels of Fins and HOMA-IR in the observation group were lower than those in the control group,and the levels of HOMA-SI were higher than those in the control group,and the difference was statistically significant(t=4.595,3.846,2.361;P＜0.05).After treatment,the levels of IL-6,TNF-α,and hs-CRP in the observation group were lower than those in the control group,and the differences were statistically significant(t=2.824,3.448,4.734,P＜0.05).The blood glucose compliance rate of the observation group was higher than that of the control group,and the difference was statistically significant(x2=4.895,P＜0.05).The difference in the incidence of hypoglycemia between the two groups was not statistically significant(x2=1.618,P＞0.05).Conclusion:Glycine insulin combined with Novolin r in the treatment of T2DM patients can improve the insulin function of the patients,control their blood glucose level and microinflammatory state of the body,and improve their blood glucose pass rate.
Type 2 diabetesInsulin glargineNovolin rBlood sugarInsulin function
万方数据
维普
