Analysis of Rifampicin Resistance Screening Among High-risk Groups for Drug-resistant Tuberculosis in Huairou District of Beijing from 2011 to 2020
Objective:To understand the rifampicin resistance status of drug-resistant tuberculosis high-risk population in Huairou District of Beijing by screening drug-resistant tuberculosis high-risk population.Methods:Screening of drug-resistant tu-berculosis high-risk groups among tuberculosis patients registered for management from 2011 to 2020 was enumerated,including screening subjects,tuberculosis culture and drug sensitivity tests,and rifampicin resistance was analyzed in drug-resistant high-risk groups.Results:From 2011 to 2020,a total of 130 cases of rifampicin-resistant high-risk groups were registered in Huairou District,Beijing,and 130 cases of resistance screening were completed,with a screening rate of 100.00%.The rate of labo-ratory contamination was 3.08%,with a smear-penetration rate of 34.62%,mainly in first-treatment patients whose sputum smears or cultures remained positive after 2 months of treatment or more.There were 81 cases of culture-positive drug-resistant tuberculo-sis in the high-risk group,with mycobacteria identified as Mycobacterium tuberculosis in 75 cases,and rifampicin resistance was detected in 23 cases,with a detection rate of 30.67%,which was significantly higher than 3.33%of the rifampicin-resistant detec-tion rate in the initially culture-positive TB patients in the same period of time,and the difference was statistically significant(x2= 40.82,P＜0.05).Conclusion:Huairou District,Beijing,has been actively carrying out surveillance so that rifampicin-resistant tu-berculosis can be effectively managed and treated,with early detection and treatment,avoiding poverty and returning to poverty,and more importantly,effectively curbing the risk of the spread of rifampicin-resistant tuberculosis,and minimizing the hazards to people's health.
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