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运动疗法对干燥综合征患者焦虑、抑郁情绪及免疫功能的影响研究

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目的:探究运动疗法对干燥综合征患者焦虑、抑郁情绪及免疫功能的影响.方法:选择2019年1月—2022年1月扬州大学建湖临床医学院风湿肾脏科收治的102例干燥综合征患者作为研究对象,根据治疗方案的不同将其分为研究组和对照组,每组各51例.对照组患者给予风湿科常规干预,研究组患者给予运动疗法和风湿科常规干预.采用医院焦虑抑郁量表(HADS)对两组患者焦虑、抑郁情绪进行评定,对两组患者治疗前及治疗3个月后的免疫功能进行评价,对比两组患者并发症发生情况.结果:治疗后,两组患者HADS评分较治疗前均降低,且研究组患者低于对照组患者,差异有统计学意义(t=13.156,P<0.05).治疗后,两组患者CD3+、CD4+均升高,研究组患者CD3+、CD4+细胞分数均高于对照组患者,差异有统计学意义(t=2.123、6.074,P<0.05).研究组患者并发症总发生率低于对照组患者,差异有统计学意义(χ2=4.320,P<0.05).结论:运动疗法应用于干燥综合征患者中,可有效改善患者焦虑、抑郁情绪,提高其免疫功能,降低其并发症发生率.
Study on the Effect of Exercise Therapy on Anxiety,Depression and Immune Function in Patients with Dry Syndrome
Objective:To investigate the effects of exercise therapy on anxiety,depression and immune function in patients with dry syndrome.Methods:102 cases of patients with dry syndrome admitted to the hospital from January 2019 to January 2022 were selected as the study subjects,and they were divided into the study group and the control group according to the difference in treatment programs,with 51 cases in each group.The control group was given routine intervention in rheumatology,and the study group was given exercise therapy and routine intervention in rheumatology.The Hospital Anxiety and Depression Scale(HADS)scale was used to assess the anxiety and depression of the patients,the immune function of the two groups was evaluated before and after 3 months of treatment,and the occurrence of complications during the treatment period was compared between the two groups.Results:After treatment,HADS scores were all lower than before treatment,and the study group was lower than the control group,and the difference was statistically significant(t=13.156,P<0.05).After treatment,CD3+ and CD4+ were elevated in both groups,and the CD3+ and CD4+ cell scores of the study group were higher than those of the control group,and the difference was statistically significant(t=2.123,6.074;P<0.05).The total complication rate of the study group was lower than that of the control group,and the difference was statistically significant(χ2=4.320,P<0.05).Conclusion:Exercise therapy applied to patients with dry syndrome can effectively improve their anxiety and depression,improve their immune function,and reduce their complication rate.

Exercise therapyRoutine nursing in rheumatology departmentPatients with Sjogren's syndromeAnxiety and depressionImmunity

刘莉、陈其元、尤新新

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扬州大学建湖临床医学院风湿肾脏科,江苏 盐城 224700

运动疗法 风湿科常规干预 干燥综合征患者 焦虑抑郁情绪 免疫功能

江苏省社会科学基金项目

18TYB004

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(6)
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