Objective:To investigate the clinical outcomes of vascular ultrasound versus traditional puncture placement of central venous catheter(CVC)in gynecologic surgical patients.Methods:63 gynecological surgery patients admitted to the hospital from April 2018 to May 2019 who had CVCs placed according to the traditional operation method were selected as the control group,and 54 gynecological surgery patients admitted from August 2020 to July 2021 who had CVCs placed by using ultrasound guidance together with Sedinger's technique were selected as the observation group.The difference in the rate of successful puncture and complications(at the time of puncture and during retention)was compared between the two groups.Results:The puncture success rate and one-needle puncture success rate of the observation group were higher than those of the control group,and the differences were statistically significant(χ2=150.22,148.11;P<0.05).The complication rate at the time of puncture and the complication rate during retention were lower in the observation group than in the control group,and the difference was statistically significant(χ2=149.37,149.00;P<0.05).The puncture time of the observation group was shorter than that of the control group,and the difference was statistically significant(t=-79.41,P<0.05).Conclusion:Vascular ultrasound with the Seidinger technique for CVC puncture can improve the success rate of puncture in gynecologic surgery patients and reduce their complication rate,thus improving patient satisfaction and ensuring medical safety.