黑龙江医学2024,Vol.48Issue(6) :757-759.DOI:10.3969/j.issn.1004-5775.2024.06.035

1例嵌合抗原受体T细胞免疫疗法患者的护理

Nursing Care of 1 Patient with Chimeric Antigen Receptor T-cell Immunotherapy

陈芳 李梦莉 李媛媛
黑龙江医学2024,Vol.48Issue(6) :757-759.DOI:10.3969/j.issn.1004-5775.2024.06.035

1例嵌合抗原受体T细胞免疫疗法患者的护理

Nursing Care of 1 Patient with Chimeric Antigen Receptor T-cell Immunotherapy

陈芳 1李梦莉 1李媛媛1
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作者信息

  • 1. 湖南省肿瘤医院淋巴瘤血液内科,湖南 长沙 410006
  • 折叠

摘要

本研究对1例接受嵌合抗原受体T细胞免疫疗法(CAR-T)治疗患者的护理体会进行概述.护理要点:CAR-T细胞成功采集、清淋化疗减轻化疗副反应、CAR-T细胞顺利输注、CAR-T细胞输注后血细胞减少预防感染,细胞因子释放综合征的观察、神经毒性的观察与护理,肠穿孔的观察与护理,心理护理,营养指导,出院宣教及延续性护理等.经过精心的护理,患者CAR-T细胞正常扩增,30 d后复查PET/CT显示肿瘤已经完全缓解,患者后期随访未出现不良反应.

Abstract

The study provides an overview of the nursing experience of one patient treated with chimeric antigen receptor T-cell immunotherapy(CAR-T).Nursing key points are as follows:successful collection of CAR-T cells,clear lymphatic chemotherapy to reduce chemotherapy side effects,smooth infusion of CAR-T cells,prevention of infection by hematopoiesis after CAR-T cell infusion,observation of cytokine release syndrome,observation and nursing care of neurotoxicity,observation and nursing care of intestinal perforation,psychological nursing care,nutritional guidance,discharge mission and continuity of care,and so on.After careful care,the patient's CAR-T cells expanded normally,and follow-up PET/CT after 30 d showed that the tumor had completely resolved.The patient had no adverse reactions in the late follow-up.

关键词

嵌合抗原受体T细胞免疫疗法/细胞疗法/护理/血细胞减少/细胞因子释放综合征

Key words

CAR-T/Cell therapy/Nursing/Hemopenia/Cytokine release syndrome

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出版年

2024
黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
参考文献量13
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