Effectiveness and Safety Analysis of Epidural Anesthesia for Lower Uterine Segment Cesarean Delivery Assisted by Different Doses of Midazolam
Objective:To observe the effect and safety of different doses of midazolam on epidural anesthesia for lower uterine segment cesarean delivery.Methods:120 cases of women who underwent lower uterine segment cesarean section treatment in the hospital from March 2021 to June 2022 were selected as the study subjects,and were divided into the observation group and the control group with the lottery method,with 60 cases in each group.Epidural anesthesia was implemented in both groups,the control group was assisted with regular dose of midazolam,and the observation group was assisted with small dose of midazolam.The intraoperative and postoperative analgesic effects,preoperative and postoperative microcirculatory function,postoperative awakening quality and the occurrence of adverse events were compared between the two groups.Results:Postoperatively,the blood oxygen saturation(SaO2)and arterial partial pressure of oxygen(PO2)of the observation group were higher than those of the control group,and the arterial partial pressure of carbon dioxide(PaCO2)was lower than those of the control group,and the differences were statistically significant(t=3.030,2.897,3.353;P＜0.05).Under different anesthesia regimens,the awakening time of the observation group was lower than that of the control group,and the difference was statistically significant(t=5.205,P＜0.05).Under different anesthesia regimens,the incidence of adverse events after awakening in the observation group was lower than that in the control group,and the difference was statistically significant(χ2=7.048,P＜0.05).Conclusion:Different doses of midazolam-assisted epidural anesthesia have significant intraoperative and postoperative analgesic effects on women undergoing cesarean section in the lower uterine segment,and none of them significantly affects the quality of patients'awakening.However,in comparison,a small dose of midazolam can shorten patients'postoperative awakening time,have less impact on patients'microcirculatory function,and have lower risk of postoperative adverse events.
Cesarean section of lower segment of uterusMidazolamEpidural anesthesiaAnalgesic effectAnesthesia safety
NETL
NSTL
万方数据
维普
