Value of Rapid Field Evaluation Combined with Ultrafine Bronchoscopy for the Diagnosis of Infectious Lesions in Peripheral(1/3)Lungs
Objective:To investigate the value of rapid on-site evaluation(ROSE)combined with ultrafine bronchoscopy in the diagnosis of infectious lesions in peripheral(1/3)lungs.Methods:100 patients older than 15 years of age with peripheral(1/3)lung lesions detected by chest CT admitted to the hospital from January 2022 to May 2022 were selected as the study subjects,and they were randomly divided into the observation group and the control group,with 50 cases in each group.In the observation group,alveolar lavage and transbronchial lung biopsy(TBLB)were performed by applying ultrafine bronchoscopy and the specimens of alveolar lavage fluid and lung biopsy were evaluated using the ROSE technique.If the ROSE result was positive,the bronchoscopy was stopped and the alveolar lavage and biopsy specimens were sent for testing and pathology.If the ROSE result was negative,alveolar lavage,TBLB and ROSE interpretation were repeated.If the results of three consecutive ROSEs were negative,the biopsy specimens were sent to pathology after multipoint TBLB at the lesion site,and the lavage fluid was sent to tests.In the control group,after alveolar lavage and transbronchial lung biopsy under routine bronchoscopy,alveolar lavage fluid and biopsy specimens were sent directly to tests and pathology.The diagnosis rate,tracheoscopy operation time(including ROSE time in the observation group),the number of tracheoscopy operations,the detection rate of effective pathogenic microorganisms,the positive rate of pathological results,and the incidence of complications were compared between the two groups.Results:The diagnosis rate of the observation group was significantly higher than that of the control group,and the difference was statistically significant(χ2=6.453,P＜0.05).There was no statistically significant difference in the comparison of tracheoscopy operation time between the two groups(t=-0.040,P＞0.05).The number of tracheoscopic operations in the observation group was greater than that in the control group,and the difference was statistically significant(t=2.225,P＜0.05).The detection rate of effective pathogenic microorganisms in alveolar lavage fluid of the observation group was greater than that of the control group,and the difference was statistically significant(χ2=6.453,P＜0.05).The positive rate of pathological findings in the observation group was greater than that in the control group,and the difference was statistically significant(χ2=6.986,P＜0.05).No serious complications such as hemoptysis and pneumothorax occurred in both groups.Conclusion:ROSE combined with ultrafine bronchoscopy has a high diagnostic rate and few complications,and can effectively improve the detection rate of effective pathogenic microorganisms and the positive rate of pathologic results without significantly increasing the operating time of bronchoscopy,which is very safe and effective for the diagnosis of infectious lesions in peripheral(1/3)lungs.
NETL
NSTL
万方数据
维普
