Value of Blood Cell Parameters in the Evaluation of Carotid Artery Atherosclerosis in Patients with Essential Hypertension
Objective:To investigate the value of blood cell parameters in evaluating carotid artery atherosclerosis(CAS)in patients with essential hypertension.Methods 123 patients in the hospital who were diagnosed as primary hypertension from January 2021 to July 2022 were taken as the researd objcets.The baseline data and blood cell parameters were compared between patients with essential hypertension with CAS(observation group,n=63)and patients with essential hypertension with normal carotid artery(control group,n=60).Multivariate logistic regression was performed to analyze CAS-related factors in patients with primary hypertension.The predictive ability of P-Logistic prediction model,P-NLR combined with SBP prediction model,P-NLR prediction model,P-N prediction model,and P-L prediction model was evaluated by ROC curve.Results There were significant differences in the age,systolic pressure,leukocyte,neutrophils,lymphocytes and monocytes between the two groups(t=-2.70,-6.46,-2.92,-4.08,-1.29,2.70;P<0.05).Multivariate logistic regression analysis showed that systolic pressure,leukocyte and neutrophils were the independent risk factors for CAS in patients with primary hypertension(OR=1.237,1.656,0.317;P<0.05).The areas under ROC curves was 0.892 for P-NLR combined with SBP prediction model,0.875 for P-Logistic prediction model,0.792 for P-NLR prediction model,0.699 for P-N prediction model,and 0.667 for P-L prediction model.Conclusion Neutrophils and lymphocytes are related to essential hypertension complicated with CAS in blood cells.The measurement of neutrophil-lymphocyte ratio is helpful for early screening and dynamic evaluation of CAS in patients with primary hypertension.
NETL
NSTL
万方数据
维普
