首页|MRI预测乳腺非特殊型浸润性导管癌Luminal分型的临床价值

MRI预测乳腺非特殊型浸润性导管癌Luminal分型的临床价值

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目的:探讨乳腺非特殊型浸润性导管癌Luminal分型的MRI表现,为乳腺非特殊型浸润性导管癌的诊疗提供更优的选择.方法:回顾性分析2018年10月8日—2021年12月1日经样本医院手术病理证实为乳腺非特殊型浸润性导管癌的119例女性患者的临床及影像学资料.比较Luminal型和非Luminal型的临床特征及MRI影像特征.绘制ROC曲线,计算ROC曲线下的面积及截断点.结果:119例乳腺非特殊型浸润性导管癌中,Luminal型72例,非Luminal型47例.患者有无淋巴结转移、肿瘤的最大径、肿瘤形态、TIC曲线、最小表观扩散系数(apparent diffusion coefficient,ADC)值和平均ADC值比较,差异统计学意义(P<0.05).当最小ADC值和平均ADC值分别为0.851×10-3 mm2/s、0.849×10-3 mm2/s时,其特异度和敏感度分别为0.553、0.806和0.681、0.750,ROC曲线下面积分别为0.745、0.761.结论:MRI可以提高乳腺非特殊型浸润性导管癌的诊断效能,其ADC值可作为其临床及预后的重要指标,更有利于临床进行更精准的治疗.
Clinical Value of MRI in Predicting Luminal Staging of Nonspecific Invasive Ductal Carcinoma of the Breast
Objective:To investigate the MRI manifestations of Luminal staging of non-specific invasive ductal carcinoma of the breast,and to provide better options for the management of non-specific invasive ductal carcinoma of the breast.Methods:Clinical and imaging data of 119 female patients with surgical pathologically confirmed non-specific invasive ductal carcinoma of the breast from October 8,2018 to December 1,2021 were retrospectively analyzed.Clinical features and MRI imaging features of Luminal and non-Luminal types were compared.ROC curves were plotted and the area under the ROC curve and cut-off points were calculated.Results:Of the 119 cases of non-specific invasive ductal carcinoma of the breast,72 were of the Luminal type and 47 of the non-Luminal type.The difference between patients with or without lymph node metastasis,tumor maximum diameter,morphology,TIC curve,minimum apparent diffusion coefficient(ADC)value and average ADC value were statistically significant(P<0.05).When the minimum and mean ADC values were 0.851×10-3 mm2/s and 0.849×10-3 mm2/s,respectively.Their specificities and sensitivities were 0.553,0.806,0.681,0.750.The areas under the ROC curves were 0.745 and 0.761,respectively.Conclusion:MRI can improve the diagnostic efficacy of non-specific invasive ductal carcinoma of the breast,and its ADC value can be used as an important indicator of its clinical and prognostic value,which is more conducive to more accurate clinical treatment.

BreastNonspecific invasive ductal carcinomaLuminal stagingClinical value

许东、陈代辉、斯光晏、刘勇、王欧成、郭锐

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西南医科大学附属中医医院放射科,四川 泸州 646000

泸县第二人民医院,四川 泸州 646100

乳腺 非特殊型浸润性导管癌 Luminal分型 临床价值

西南医科大学-西南医科大学附属中医医院自然科学青年苗圃项目

2020XYLH-067

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(8)
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