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泌尿系肿瘤骨转移的手术治疗策略

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目的:探讨手术治疗泌尿系肿瘤骨转移患者的临床效果.方法:回顾性分析2015年7月—2021年8月西部战区总医院泌尿外科和骨科收治的20例泌尿系肿瘤骨转移患者临床资料,按照治疗方案不同分为观察组和对照组,每组各10例.对照组拒绝行手术治疗,给予镇痛等对症治疗,观察组减少镇痛药物使用并行手术治疗.患者均进行12个月随访,比较两组患者治疗后1周和末次随访疼痛评分.结果:观察组治疗后7 d及末次随访疼痛评分均低于对照组,差异有统计学意义(t=-5.018、-6.488,P<0.05).泌尿系肿瘤骨转移患者予以骨科手术治疗后,均能有效缓解一定程度的骨痛,提高患者生活质量.结论:泌尿系肿瘤骨转移的诊断需综合临床、病理、检验及免疫组化结果,积极手术治疗泌尿系骨转移不但可控制转移灶肿瘤进展,重建骨骼功能,而且能明显缓解疼痛,延长患者的寿命和改善生活质量.
Surgical Treatment Strategies of Bone Metastasis of Urinary Tumor
Objective:To explore the clinical effect of surgical treatment of bone metastasis of urinary tumor.Methods:The clinical data of 20 patients with bone metastasis of urinary tumors treated in the Department of Urology and Orthopaedics of General Hospital of the Western Theater Command PLA from July 2015 to August 2021 were retrospectively analyzed.They were divided into observation group(n=10)and control group(n=10).The control group refused surgical treatment and received symptomatic treatment such as analgesia,while the observation group reduced the use of analgesics and surgical treatment.All patients were followed up for 12 months,and the VAS scores of pain in the first week and the last follow-up were compared between the two groups.Results:The pain score of the observation group 7 days aftre treatment and the last visit was lower than that of the control group with statistically sigificant difference(t=-5.018,-6.488;P<0.05).After orthopedic surgery,the patients with bone metastasis of urinary tumor can effectively relieve bone pain and improve their quality of life.Conclusion:The diagnosis of bone metastasis of urinary tumor needs to synthesize the results of clinical,pathology,examination and immunohistochemistry.Active surgical treatment of bone metastasis of urinary system can not only control the progression of metastatic tumor and reconstruct bone function,but also relieve pain obviously,prolong the life span of patients and improve the quality of life.

Urinary tumorBone metastasisSurgical treatment

黄园顺、冉舒、李晓伟、赵友光、周婷婷、李沙丹

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西部战区总医院泌尿外科,四川 成都 610083

联勤保障部队第九四五医院泌尿外科,四川 雅安 625000

四川外国语大学医院综合门诊部,重庆 400030

泌尿系肿瘤 骨转移 手术治疗

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(9)