Objective:To investigate the effect of Montelukast combined with budesonide in children with chronic cough caused by Mycoplasma pneumoniae infection.Methods:80 children with chronic cough caused by mycoplasma pneumoniae infection admitted to the hospital from May 2021 to July 2022 were randomly divided into 2 groups,with 40 cases in each group.Control group was treated with budesonide,and experimental group was treated with montelukast combined with budesonide.The treatment situation was compared.Results:After treatment,symptom remission and hospital stay in the experimental group were shorter than those in the control group,and the difference was statistically significant(t=13.019,24.150,7.925;P＜0.05).The levels of inflammatory factors in experimental groups were better than those in control group,and the difference was statistically significant(t=20.122,7.392,15.313,20.243,19.004;P＜0.05).After treatment,the indexes above in the experimental group were lower than those in the control group,with statistically significant difference(t=4.059,7.607,11.718;P＜0.05).After treatment,the experimental group was better than the control group in lung function index,and the difference was statistically significant(t=4.044,6.081,4.153;P＜0.05).The effective rate of the experimental group was 95.0%,which was higher than that of the control group(77.5%),and the difference was statistically significant(χ2=5.165,P＜0.05).Conclusion:Montelukast combined with budesonide in the treatment of chronic cough caused by mycoplasma pneumoniae infection is effective.
MontelukastBudesonideChronic cough caused by mycoplasma pneumoniae infectionLung function
NETL
NSTL
万方数据
