首页|中医药干预反流性食管炎相关信号通路因子表达的研究进展

中医药干预反流性食管炎相关信号通路因子表达的研究进展

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反流性食管炎(RE)是胃食管反流病的一种重要亚型,发病率呈逐年升高的趋势.近年来,中医药对RE的治疗取得了良好的成效,然而RE的发病机制复杂,涉及到的通路繁多,文章主要总结以下NLRP3/Caspase-1,NF-κB、HIF-2α、P38MAPK信号通路以及经方治疗对以上通路的干预作用,为中医药治愈RE提供科学依据.
Research Progress of Chinese Medicine Intervention on the Expression of Signaling Pathway Factors in Reflux Esophagitis
Reflux esophagitis(RE)is an important subtype of gastroesophageal reflux disease,and its incidence is increasing year by year.In recent years,traditional Chinese medicine has achieved good results in the treatment of reflux esophagitis,many scholars have discussed how traditional Chinese medicine intervenes in the mechanism of RE pathway,however,the pathogenesis of RE is complex,involving a wide range of pathways.The study mainly summarizes the following NLRP3/Caspase-1,NF-κB,HIF-2α and P38MAPK signaling pathway and the intervention effect of meridian treatment on the pathway above,providing scien-tific basis for the cure of RE by traditional Chinese medicine.

Reflux esophagitisTraditional Chinese medicineSignaling pathway

王敏、王爱民、徐心怡、杨欣、吴婷婷、朱惠萍、胡绍江、孙宏文

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南京中医药大学附属苏州市中医医院,江苏 苏州 215007

苏州科技城医院中医科,江苏 苏州 215000

反流性食管炎 中医药 信号通路

2024

黑龙江医学
中华医学会黑龙江分会

黑龙江医学

影响因子:0.714
ISSN:1004-5775
年,卷(期):2024.48(11)