Effect of Invasive Mechanical Ventilation on Respiratory,Circulatory,and Cardiac Function of ICU Patients with Severe Heart Failure
Objective:To explore the application effect of invasive mechanical ventilation in ICU patients with severe heart failure(HF).Methods:86 severe HF patients admitted to ICU from June 2020 to June 2022 were selected and randomly divided into two groups,with 43 patients in each group.Control group received routine medication treatment,while the observation group received invasive mechanical ventilation treatment.The two groups were evaluated 7 days after treatment.The respiratory and circulatory function,levels of neuroendocrine factors,cardiac function,and adverse cardiovascular events between the two groups were compared.Results:After treatment,the arterial partial pressure of oxygen(PaO2)and oxygenation index(OI)in the observation group were higher than those in the control group.Partial pressure of carbon dioxide(PaCO2)and respiratory rate(RR)were lower than those in the control group,with statistically significant difference(t=3.685,5.912,5.854,4.972;P＜0.05).After treatment,the levels of aldosterone(ALD)and atrial natriuretic peptide(ANP)in the observation group were lower than the control group,while cortisol(COR)was higher than the control group,with statistically significantly difference(t=5.303,4.590,4.418;P＜0.05).After treatment,the left ventricular ejection fraction(LVEF)of the observation group was higher than the control group;and the left ventricular end systolic diameter(LVESD),left ventricular end diastolic diameter(LVEDD),and vascular resistance(SVR)were lower than the control group,with statistically significant difference(t=5.384,6.772,6.272,4.439;P＜0.05).The observation group had fewer adverse cardiovascular events compared to the control group,with statistically significant difference(χ2=4.441,P＜0.05).Conclusion:Invasive mechanical ventilation can improve respiratory and circulatory function,correct neuroendocrine factor disorders,accelerate cardiac function recovery,and reduce adverse cardiovascular events in ICU patients with severe HF.
Severe heart failureInvasive mechanical ventilationRespiratory and circulatory functionCardiac function
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