Analysis of the Diagnostic Value of Combined Detection of Serum Hcy,CTnI,TG/HDL-C,and Lp(a)in Coronary Heart Disease
Objective:To analyze the efficacy of combined detection of serum homocysteine(Hcy),cardiac troponin I(CTnI),triglyceride/high-density lipoprotein cholesterol(TG/HDL-C),and lipoprotein(a)[LP(a)]in the diagnosis of coronary heart disease.Methods:63 patients with coronary heart disease admitted to the hospital from May 2021 to May 2022 were included in the observation group.In addition,54 healthy people who underwent physical examination in the hospital at the same time were included in the control group.Venous blood was collected from the two groups,and the differences in Hcy,CTnI,TG/HDL-C,and Lp(a)were detected and compared.A receiver operating curve(ROC)was drawn to analyze the efficacy of Hcy,CTnI,TG/HDL-C and Lp(a)alone or in combination in diagnosing coronary heart disease.Results:Hcy,CTnI,TG/HDL-C,LP(a)in observation group were higher than those in control group,and the difference was statistically significant(t=21.556,35.837,11.090,45.618;P＜0.05).ROC results showed that the area under the curve(AUC)of the combined detection of Hcy,CTnI,TG/HDL-C and Lp(a)was 0.916,which was higher than the AUC of 0.807,0.869,0.846 and 0.810 of the independent detection.Conclusion:Hcy,CTnI,TG/HDL-C,and Lp(a)are abnormally expressed in the body of patients with coronary heart disease.Combined detection can be used for early diagnosis of coronary heart disease.
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