食管癌患者选择不同手术方案对机体免疫功能及预后效果的影响
Effect of Different Surgical Schemes on Immune Function and Prognosis of Patients with Esophageal Cancer
张丽 1冯杰 1王琼2
作者信息
- 1. 南阳市肿瘤医院胸外综合科,河南 南阳 473000
- 2. 南阳市中心医院胸外科,河南 南阳 473000
- 折叠
摘要
目的:分析食管癌患者临床治疗中采用不同手术方案的价值.方法:选取2019年10月-2021年8月样本医院收治的60例食管癌患者作为研究对象,按随机数表法分为对照组和观察组,每组各30例.对照组采用常规食管癌根治术治疗,观察组采用胸腔镜食管癌根治术治疗,对比两组患者并发症率、手术指标、免疫功能、满意度.结果:观察组并发症率低于对照组,差异有统计学意义(x2=4.812,P＜0.05);观察组术中出血量、手术时间、住院时间、首次排气时间较对照组均降低,差异有统计学意义(t=24.763、5.206、15.148、7.611,P＜0.05);治疗后,观察组CD4+、NK高于对照组,差异有统计学意义(t=5.168、4.618,P＜0.05);观察组满意度高于对照组,差异有统计学意义(x2=5.192,P＜0.05).结论:选择胸腔镜食管癌根治术对食管癌进行治疗可改善患者免疫功能,亦可降低术中出血量,提高患者满意度.
Abstract
Objective:To analyze the value of different surgical plans in the clinical treatment of esophageal cancer patients.Methods:60 patients with esophageal cancer were selected from October 2019 to August 2021 in the hospital were selected as the research objects.According to random number table method,they were divided into two groups,with 30 cases in each group.Control group was treated with routine radical esophagectomy,and observation group was treated with thoracoscopic radical esophagectomy.The complication rate,surgical indexes,immune function and satisfaction were compared between the two groups.Results:The complication rate in the observation group was lower than that in the control group(x2=4.812,P＜0.05).Intraoperative blood loss,operation time,hospital stay and first exhaust time in the observation group were lower than those in control group(t=24.763,5.206,15.148,7.611;P＜0.05).CD4+and NK in observation group were higher than those in control group(t=5.168,4.618;P＜0.05).The satisfaction of observation group was higher than that of control group,and the difference was statistically significant(x2＝5.192,P＜0.05).Conclusion:Choosing thoracoscopic radical esophagectomy for esophageal cancer can improve the immune function of patients.It can also reduce the amount of intraoperative bleeding,and improve patient satisfaction.
关键词
胸腔镜/食管癌根治术/免疫功能Key words
Thoracoscopy/Radical esophagectomy/Immunity引用本文复制引用
出版年
2024
NETL
NSTL
万方数据